Given below is the name of a polypeptide Valyllysylalanylhistidylaspartylphenylalanylglycylglutamate The average pKas of different groups/side chains are shown in the table below: Group/amino acid side chain pKa C-terminus 3.5 D 3.9 E 4.1 H 6.0 8.4 Y 10.5 K 10.5 R 12.5 N-terminus 9.0 What is the total charge of this molecule at pH 5? ( Select] What is the total charge of this molecule at pH 9.5? [ Select ] >

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Given below is the name of a polypeptide
Valyllysylalanylhistidylaspartylphenylalanylglycylglutamate
The average pKas of different groups/side chains are shown in the table below:
Group/amino acid side chain
pKa
C-terminus
3.5
3.9
E
4.1
H
6.0
8.4
Y
10.5
K
10.5
R
12.5
N-terminus
9.0
What is the total charge of this molecule at pH 5? [ Select ]
What is the total charge of this molecule at pH 9.5? [ Select]
>
>
Transcribed Image Text:Given below is the name of a polypeptide Valyllysylalanylhistidylaspartylphenylalanylglycylglutamate The average pKas of different groups/side chains are shown in the table below: Group/amino acid side chain pKa C-terminus 3.5 3.9 E 4.1 H 6.0 8.4 Y 10.5 K 10.5 R 12.5 N-terminus 9.0 What is the total charge of this molecule at pH 5? [ Select ] What is the total charge of this molecule at pH 9.5? [ Select] > >
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