GENETICS AND FAST-TWITCH MUSCLES The gene ACTN3 encodes a protein that functions in fast-twitch muscles. People can be classified according to which genotype of this gene they have, RR, RX, or XX, and also according to which genetic allele they have, R or X. The study¹ described here, examines the association between this gene and different subgroups of the population. All participants in the study live in Australia. The earlier exercises only included the control group. Gender and ACTN3 Genotype We know that sprinters are more likely to have allele R and genotype RR versions of the ACTN3 gene, which makes these versions associated with fast-twitch muscles. Is there an association between genotype and gender? Computer output is shown for this chi- square test, using the control group in the study. In each cell, the top number is the observed count, the middle number is the expected count, and the bottom number is the contribution to the chi-square statistic. What is the p-value? p-value = i Male Female RR 40 40.26 0.002 88 87.74 0.001 RX 73 128 69.20 0.208 147 150.80 0.096 XX 21 24.54 0.509 Total Chi-Sq = 1.050, DF = 2, P-Value = 0.592 220 57 53.46 0.234 78 Total 134 292 426
GENETICS AND FAST-TWITCH MUSCLES The gene ACTN3 encodes a protein that functions in fast-twitch muscles. People can be classified according to which genotype of this gene they have, RR, RX, or XX, and also according to which genetic allele they have, R or X. The study¹ described here, examines the association between this gene and different subgroups of the population. All participants in the study live in Australia. The earlier exercises only included the control group. Gender and ACTN3 Genotype We know that sprinters are more likely to have allele R and genotype RR versions of the ACTN3 gene, which makes these versions associated with fast-twitch muscles. Is there an association between genotype and gender? Computer output is shown for this chi- square test, using the control group in the study. In each cell, the top number is the observed count, the middle number is the expected count, and the bottom number is the contribution to the chi-square statistic. What is the p-value? p-value = i Male Female RR 40 40.26 0.002 88 87.74 0.001 RX 73 128 69.20 0.208 147 150.80 0.096 XX 21 24.54 0.509 Total Chi-Sq = 1.050, DF = 2, P-Value = 0.592 220 57 53.46 0.234 78 Total 134 292 426
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
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