For the drug indicated below, calculate an approximate value for the therapeutic index and safety factor. 100- Death Hypnosis 00 60- 40- LD ED ED 50 100 LD 99 50 50 200 400 800 1000 Dose (mg) % of Individuals Responding

Q: CONVERSIONS FOR REFERENCE: 2.2 lb = 1 kg 1t 5 mL 1 gr 60 mg 1T 15 ml 1 ml 1 ml 15 gtt 1 oz 30 ml 1…

A: Disclaimer: As per Bartleby guidelines, we will solve only the first question. Please repost the…

Q: Calculate the I & O from 7 am-3 pm. A client has IV fluids D5 ½ NS with 20 mEq potassium chloride…

A: An important piece of data regarding a patient's fluid and electrolyte balance is provided by the…

Q: NaCl 10 mEq per hour, for a patient with hyponatremia. Available: NaCl 50 mEq per 500 mL D5 ½ NS.…

A: ordered dose of NaCl= 10 mEq /hr available prepration=50 mEq per 500 ml D5/2 NS we have 50 mEq in…

Q: Dalteparin sodium has been prescribed for a patient with unstable coronary artery disease. Use the…

A: Let's delve deeper into how to determine the volume of dalteparin sodium to administer per dose…

Q: Order: Morphine sulfate 7.5 mg, subcut, q4h, PRN Child's weight: 84 lb Recommended dose range: 0.1…

A: According to the label on the vial, the vial contains 5 mg drug in 1 ml. The order prescribes 7.5 mg…

Q: Order: Ceftriaxone 900 mg IV q.12h in 50 mL 5% Dextrose and Water IV solution Supply: Ceftriaxone 1…

A: Answer.  Given data :----  Ordered ceftriaxone = 900 mg.  Available drug concentration = 100 mg /…

Q: The medication order reads: 1000 mL of D/5/W with 1,000 mg of a drug at 1 mg/min. With a drop factor…

A: Based on how many drips (gtt) are given to the patient per minute, the pace of an intravenous…

Q: Medication order reads: Fluconazole 200 mg po tid. Supply on hand: Fluconazole 200 mg/5 mL. Give mL

A: The nurse should be careful while administering the medication and follow "5 Right's" before…

Q: Order: acetaminophen (Tylenol) 80 mg PO Q4H PRN fever Patient 20.5 kg; 6 years old Supply: 80 mg…

A: Tyelenol is the drug that is taken for fever and pain relief. Correct dosage of any drug should be…

Q: Mr. Mitch Igan, 60YOM, had a CVA. He is NPO and a NGT was placed. IVF are at 75 mL/hr. • Height is 5…

A: Introduction to Enteral Nutrition (EN)Enteral nutrition (EN) is a method of providing nutrition…

Q: The recommended dose for dilantin is 4-8 mg/kg/day q12h.  The child weighs 11 pounds. Order:…

A: The nurse should consider the "5 Rights” of the medication before administering the medication. They…

Q: A child weighs 20 kg and the recommended dose of Drug Z is 5 mg per kg.  Determine the total dose of…

A: A drug is a chemical substance that causes physiological responses in the body. Usually different…

Q: The recommended single dose for acetaminophen is 10.0 to 15.0 mg/kg of body weight for adults. Using…

A: Maximum and minimum dosage calculation was done to make sure that the drug is administered safely to…

Q: An infant weighing 11 lbs. is ordered erythromycin ethylsuccinate 62.5 mg by mouth every 6 hours.…

A: Drug: Any chemical substance that alters physical or emotional changes through its chemical action…

Q: a placebo-controlled study, 10 healthy subjects were given oral triazolam 0.5 mg before and  after…

A: A. Rifampicin induces the activity of drug-metabolizing enzymes, including cytochrome P450 3A4…

Q: Your patient, Covey, has her first day today. She is 91 years old and has an extreme fear of…

A: It is used in older patients with cardiac, respiratory and other disease like vascular diseases and…

Q: he drug reference indicates 15mg/kg/day q8h of kanamycin is a safe dose range.   Order: Kanamycin…

A: Label indicates that the vial contains 75 mg of drug per 2 ml. Maximum dose of drug is 15 mg/kg/day.…

Q: they do have significant pharmacological differences.

A: Ibuprofen and naproxen are both non-selective NSAIDs, meaning they inhibit both COX-1 and COX-2…

Q: Based on the treatment algorithms of the international hypertension guidelines, what is the target…

A: In the clinical condition of tuberculosis or TB, almost 69% of the population does not show any…

Q: Order: morphine 2 mg SQ Q 3 hours PRN pain Patient: 14 kg; 3 years old Supply: 200mcg/mL vial…

A: Order:morphine 2 mgSQQ 3 hoursPRN painPatient: 14 kg;3 years oldSupply: 200mcg/mL vialLiterature:…

Q: For each of the three drugs in the above order, please calculate the dose in mg and the infusion…

A: A drug is a chemical substance that is administered into the body according to the dosage…

Q: A nurse is preparing to administer heparin 15 units/kg/hr by continuous IV infusion to a client who…

A: Given:Heparin dose = 15 units/kg/hrClient weight = 86 kgHeparin concentration = 25,000 units in 500…

Q: A drug with the lower ED50 value is the more effective drug. false true

A: A drug’s efficacy is tested in vitro and in vivo as well. Its different dose levels are assessed to…

Q: Calculate a new value from the following IV prescription. "Give 350 mL D10W IV over 4 hours"…

A: The prescription states to give 350 mL of D10W IV over a period of 4 hours. D10W stands for Dextrose…

Q: practitioner prescribed 200 mg of ibuprofen PO q6h PRN pain. The nurse has available 100 mg/ 5 ml of…

A: Ordered dose =200mg

Q: #2

A: This drug is used to treat irregular heart beat and it should be given according to the doctor's…

Q: A 38 lb child is prescribed phenobarbital 10 mg orally every 12 hours. The nurse has phenobarbital…

A: Child's weight is 38 lbprescribed dose of phenobarbital is 10mg / 12 hrThe SDR is 1-6 mg/kg daily in…

Q: a. What flow rate will be set on the infusion pump for 0.3 mg/ kg/ hr? DA equation: Evaluation: b.…

A: A) The client should get 0.3mg/kg/hour. Patient weight:  75kgs. Dose for this client = 0.3mg x…

Q: Order: Adriamycin 50 mg/m2 in three individual doses mixed with 1000 mL normal saline solution per…

A: The formula for BSA(Body Surface Area) BSA= √height(in cm)×weight (kg)/3600

Q: Why do we treat acute trauma with ice?  Please keep brief - 4 sentences/dot points max.

A: Hi, Thanks For Your Question.  Answer : In The Case Of Acute Trauma Or Injuries, Ice Packs And…

Q: Ordered: 0.03 g/kg q6h Weight: 60lb (round weight to the nearest tenth) On hand: 200 mg/5mL How many…

A: Ordered drug = 0.03 gm / kg / q 6 h. weight of patient = 60 pounds. Available drug concentration =…

Q: prescribed morphine 2 mg subcutaneous every 6 hours.

A: Given data:Child's weight: 46 lbsMorphine prescription: 2 mg subcutaneous every 6 hoursMorphine: 1…

Q: amount

A: Type of Athlete: Anaerobic or Resistance-Trained AthleteSupplement Stack: Creatine Monohydrate and…

Q: According to the assigned clinical case, determine the maintenance plan and rehydration fluids (if…

A: Data given is as follows:Patient: cat Age: 5 yrsWeight: 10 poundsFor maintenance calculation in…

Q: At the peak drug concentration in the plasma, the rate of drug absorption is higher than the rate of…

A: A drug is injected intravascularly directly enter into systemic circulation. Majority of drugs…

Q: The steady-state amikacin concentration is 2 mg/L, the clearance is 0.1 L/min, if the amikacin is to…

A: Amikacin: Amikacin is an antibiotic that belongs to the class of drugs known as aminoglycosides. It…

Q: 1.5 mg po t.i.d. How many 0.5 mg tablets of this antianxiety drug will you administer to the patient…

A: Given,  Amount of drug to be given to the patient = 1.5 mg PO t.i.d. Which means 1.5 mg is to be…

Q: A patient is taking acetaminophen (Tylenol) 325 mg, 2 tablets PO every 6 hours (4 doses in 24hrs).…

A: Acetaminophen is a para-aminophenol derivative used to treat mild pain and fever. The drug belongs…

Q: Valsalva maneuver

A: It is very important to be physically active and to maintain the regular exercises. The exercise…

Q: The regimen for a drug is as follows: 5mcg/kg q week x 2, then 7mcg/kg q 2 weeks. Calculate the dose…

A: The specific amount of drug administered at a time is called a dose. The frequency of drug…

Q: Two twins with identical physiology, biochemistry, weight and height are exposed to a total of 5…

A: the size of particulate matter (PM) can indeed affect its toxicity. Smaller particles, such as…

Q: A nurse is preparing to administer penicillin G intravenous bolus to a child. What is the lowest…

A: As a nurse its her responsibility to remember the formula while calculating the drug to avoid…

Q: A nurse is preparing to administ toxicillin 320 mg PO every 12 hr to an infant. The amount available…

A: Amoxicillin in an antibiotic drug. It belongs to the family of penicillin drugs and is used to treat…

Q: What is the normal value? What is the abnormal range? What does it mean with a low value? What does…

A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. Please re-submit the question and…

Q: EPO injections, used as an ergogenic approach, are a risk to health, due to the significant…

A: EPO is Erythropoietin injections. Increase in blood viscosity means that the blood becomes thick.

Q: The pediatric nurse practitioner orders Dilantin 40 mg po bid for a child weighing 14 lb 7oz.  The…

A: Dilantin is the name given to a drug called phenytoin and it is mostly used to treat people that…

Q: zinioq.nislqx3 H) Order: Amoxicillin 0.5 g for a sick child every 8 hours. Amoxicillin available is…

A: Amoxicillin is a type of antibiotic that is used to treat a wide variety of bacterial infections. It…

Clinical Pharmacology

Pharmacology is a discipline of medicine that studies how medications interact with the systems and processes of living organisms, focusing on drug action mechanisms as well as therapeutic and other purposes.