For each non-human animal, take a highlighter and mark any amino acids that are different than the human sequence. When you finish, record how many differences you found in the table on the next page. 42 43 44| 46 47 49 50 53 54 55 56 57 Human Q A Y A K N K Chicken Q A E F D K K Horse Tuna F E S S. A D K K G A F K K G Frog Q A A F K K Shark Q А Q F K K G Turtle Q A E F S E K N. K G Monkey Q A Y T A K N K Rabbit Q A V F D K K 58 60 61 62 63 64 65 66 100 101 102 103 104 Human G E D T M E K A N E Chicken G T. M A K Horse T K T L M E K A Tuna V N E T L R E K A Frog G E T M S A C S K Shark T Q Q A A S Turtle G A T K Monkey T G E E K A T N E Rabbit E M E K A N Molecular Biology Summary Questions 3. Based on the Cytochrome C data, which organism is most closely related to humans? 4. Do any of the organisms have the same number of differences from human Cytochrome C? In situations likethis, how would you decide which is more closely related to humans?

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Molecular Biology
Cytochrome c is a protein found in mitochondria. It is used in the study of evolutionary relationships because
most animals have this protein. Cytochrome c is made of 104 amino acids joined together.
Below is a list of the amino acids in part of a cytochrome protein molecule for 9 different animals. Any
sequences exactly the same for all animals have been skipped.
For each non-human animal, take a highlighter and mark any amino acids that are different than the human
sequence. When you finish, record how many differences you found in the table on the next page.
42
43
44
46
47
49
50
53
54
55
56
57
Human
A
Y
S
T.
А
K
N
G
Chicken
Q
A
E
S
T.
K
K
G
Horse
A
P
D
K
N
K
G
Tuna
Q
E
F
Frog
A
А
S
D
K
N
K
G
Shark
A
Q
T.
D
K
S
K
Turtle
Q
A
E
F
K
N
K
G
Monkey
Q
А
Y
T.
K
Rabbit
Q
А
V
F
D
K
N
K
G
58
60
61
62
63
64
65
66
100
101
102
103
104
Human
G
E
D
M
E
K
A
T
N
E
Chicken
G
E
D
M
D
A
Horse
T
K
E
E
T
L
M
E
K
A
T
N
E
Tuna
V
E
T
L
R
E
K
Frog
T.
G
E
T
L
M
E
S
A
K
Shark
Q
E
L
R
K
A
A
Turtle
T
G
E
E
L
M
D
A
S
K
Monkey
E
L
M
E
K
A
T
E
Rabbit
G
E
L
M
E
K
A
N
E
Molecular Biology - Summary Questions
3. Based on the Cytochrome C data, which organism is most closely related to humans?
4. Do any of the organisms have the same number of differences from human Cytochrome C?
In situations likethis, how would you decide which is more closely related to humans?
Transcribed Image Text:Molecular Biology Cytochrome c is a protein found in mitochondria. It is used in the study of evolutionary relationships because most animals have this protein. Cytochrome c is made of 104 amino acids joined together. Below is a list of the amino acids in part of a cytochrome protein molecule for 9 different animals. Any sequences exactly the same for all animals have been skipped. For each non-human animal, take a highlighter and mark any amino acids that are different than the human sequence. When you finish, record how many differences you found in the table on the next page. 42 43 44 46 47 49 50 53 54 55 56 57 Human A Y S T. А K N G Chicken Q A E S T. K K G Horse A P D K N K G Tuna Q E F Frog A А S D K N K G Shark A Q T. D K S K Turtle Q A E F K N K G Monkey Q А Y T. K Rabbit Q А V F D K N K G 58 60 61 62 63 64 65 66 100 101 102 103 104 Human G E D M E K A T N E Chicken G E D M D A Horse T K E E T L M E K A T N E Tuna V E T L R E K Frog T. G E T L M E S A K Shark Q E L R K A A Turtle T G E E L M D A S K Monkey E L M E K A T E Rabbit G E L M E K A N E Molecular Biology - Summary Questions 3. Based on the Cytochrome C data, which organism is most closely related to humans? 4. Do any of the organisms have the same number of differences from human Cytochrome C? In situations likethis, how would you decide which is more closely related to humans?
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