EXPLAIN WHY? Ciprofloxacin (Cipro) is a fluoroquinolone antibotic. Its elimination half life and the apparnt volume of distribution are 4 h and 2,25 L/kg respectively. The IV bolus administration of ciprofloxacin yielded the plasma concentration 1,048 microgram/mL at 6 h. Determine the administered dose of Cipro? a. 2,963 mg/kg b. 6,667 mg/kg c. 2,963 microgram/mL d. 5.0 mg Levofloxacin is a broad spectrum antibotic. It is reported that it is completely removed in an unchanged from the body and its elimination half life is 7 h. Determine the amount of levofloxacin eliminated in urine a
EXPLAIN WHY?
Ciprofloxacin (Cipro) is a fluoroquinolone antibotic. Its
elimination half life and the apparnt volume of distribution are 4
h and 2,25 L/kg respectively. The IV bolus administration of
ciprofloxacin yielded the plasma concentration 1,048
microgram/mL at 6 h. Determine the administered dose of
Cipro?
a. 2,963 mg/kg
b. 6,667 mg/kg
c. 2,963 microgram/mL
d. 5.0 mg
Levofloxacin is a broad spectrum antibotic. It is reported that it
is completely removed in an unchanged from the body and its
elimination half life is 7 h. Determine the amount of
levofloxacin eliminated in urine at 10 h following IV bolus
administration of 6,25 mg/kg dose to a patient weighing 80 kg.
a. 185,75 mg
b. 314,25 mg
c. 314,25 mg/kg
d. 18,57 mg
The numerical value of the term e
-kt at a time equal
to 3 half lives of a drug will always be equal to
a. 0.5
b. 0.75
c. 0.05
d. 0.125
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