Explain how substitutions at the 5-position of phenobarbital increase the compound's lipophilicity.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter10: Alcohols
Section: Chapter Questions
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Explain how substitutions at the 5-position of phenobarbital increase the compound's lipophilicity.

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