Experiment 2: H₂N SYNTHESIS OF A PROTECTED AMINO ACID OH +gbla OH Learning outcomes: 1. Solubility of compounds in different environment 2. Track product through extraction in separatory funnel 3. TLC Background Protection of one of the functional groups of an amino acid, allows for selective reactivity in coupling reactions (SEE LECTURE NOTES). Pre-practical "MUST DO" to be included in your lab-book: 1. Calculate MW of all reagents, moles and theoretical yield 2. Reaction mechanism 3. What is the role of NaOH? 4. An R+ is given for the product, how will it change if the eluent mixture was more polar?

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Experiment 2:
H₂N
SYNTHESIS OF A PROTECTED AMINO ACID
OH
+gbla
OH
Learning outcomes:
1. Solubility of compounds in different environment
2. Track product through extraction in separatory funnel
3. TLC
Background
Protection of one of the functional groups of an amino acid, allows for selective reactivity in
coupling reactions (SEE LECTURE NOTES).
Pre-practical "MUST DO" to be included in your lab-book:
1. Calculate MW of all reagents, moles and theoretical yield
2. Reaction mechanism
3. What is the role of NaOH?
4. An R+ is given for the product, how will it change if the eluent mixture was more polar?
Transcribed Image Text:Experiment 2: H₂N SYNTHESIS OF A PROTECTED AMINO ACID OH +gbla OH Learning outcomes: 1. Solubility of compounds in different environment 2. Track product through extraction in separatory funnel 3. TLC Background Protection of one of the functional groups of an amino acid, allows for selective reactivity in coupling reactions (SEE LECTURE NOTES). Pre-practical "MUST DO" to be included in your lab-book: 1. Calculate MW of all reagents, moles and theoretical yield 2. Reaction mechanism 3. What is the role of NaOH? 4. An R+ is given for the product, how will it change if the eluent mixture was more polar?
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