Draw a reaction with reactant(s) and expected product(s) for each of the 6 alkyl halides  in the SN2 reaction. If no product formed for any of the reactions indicates no reaction . In SN2  12% sodium iodide in acetone  was used to react with 6 alkyl halids 1-chlorobutane,  2-chlorobutane,  Allyl chloride,  2-chloro-2-methylpropane,  1-chloro-2-methylpropane,  2-bromobutane

Q: Which of the following lists functional groups in order of increasing reactivity towards…

A: The reactivity of the acyl compounds towards nucleophiles depends on the partial positive charge…

Q: The compound below is treated with N-bromosuccinimide (NBS) in the presence of light. Draw both…

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Q: A student wanted to know whether the greater proximity of the ucleophile to the C-2 carbon in the…

A: The reaction of HCl with 2-methyl-1,3-cyclohexadiene will form 1,2-addition product and 1,4-addition…

Q: Nitration involves the use of HNO3 and H₂SO4 to generate NO₂+. The aromaticity rule (4n+2) refers to…

A: The statements given are Nitration involves the use of HNO3 and H2SO4 to generate NO2+. The…

Q: Draw structural formulas for the major product(s) formed by reaction of 3-hexyne with each of these…

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Q: Complete the synthesis of ethyl (E)-2,2,4-trimethyl-3-oxo-5-phenylpent-4-enoate from the starting…

A: Ester molecules can undergo substitution or nucleophilic addition reactions. The alpha hydrogen,…

Q: Which of the following alkyl halides will react most rapidly in an E2 reaction? CH3 H₂C I C1 CH3 II…

A: E2 reaction  ----> 1) tertiary alkyl halide give more rapid E2 than after secondary alkyl halide…

Q: 1. The following reaction will proceed through both the SN1 and E1 mechanisms. Use curved arrows to…

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Q: Offer an explanation for the observation that 4-chloropyridine is more reactive toward nucleophiles…

A: The reason why 4-chloropyridine is more reactive towards nucleophiles when compared to…

Q: Alkyl halides 1-chlorobutane 2-chlorobutane Allyl chloride 2-chloro-2-methylpropane…

A: Allyl chloride    The electronegativity order of hybridized carbons is sp>sp2>sp3.  So in an…

Q: DBU faster reaction Br DBU slower reaction Br

A: In E2 (Bimolecular elimination) reactions in single step the reaction completes. Both the leaving…

Q: Predict the starting alkyl bromide that would produce the product shown in the SN1 reaction. Assume…

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Q: which of the following solvents will best promote a nucleophilic reaction between NaCN and…

A: Polar aprotic solvents such as DMSO, acetone, DMF and acetonitrile are often chosen for SN2…

Q: Predict the starting alkyl chloride that would produce the product shown in the SN1 reaction. Assume…

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Q: For each of these compounds, draw an alkyl halide that can be used to produce it in an SN1 reaction.…

A: Tertiary alkyl halide reacts with solvent (water or methanol) to give a solvolysis reaction. The…

Q: CH₂CH₂BrH₂C=CHC(Br) CH 3 H₂C=CHBr CH3CH (Br) Q13

A: Sn1 reaction proceeds through a carbocation intermediate. So the alkyl halide which gives a stable…

Q: a) 1- Chlorohexane or cyclohexyl chloride. c) 2- Chloropentane or 2- Fluoropentane d) 2- Bromo - 2 -…

A: Solution: The answer of all the questions are shown below with brief explanation ---

Q: Rank the primary, secondary, tertiary, and aryl halides in terms of reactivity with the nucleophile.…

A: Nucleophilic substitution biomolecular reaction (SN2): The bimolecular nucleophilic substitution…

Q: The reagent is a Grignard reagent and is a source of CH3CH2- anions. Which epoxide carbon will the…

A: The epoxides are strained and undergoes nucleophilic addition reaction with Grignard Reagent.

Q: Saturated sodium iodide in acetone test for primary and secondary alkyl halides Sodium iodide is…

A: Given Reactant  Primary Alkyl halide (either Chloride or Bromide) contains 15 carbon atoms Reagent…

Q: Which of these compounds is expected to react the fastest in an Sn1 reaction? CH30 CH2BR O2N- CH2BR…

A: Benzyl bromide gives SN1 reaction with the nucleophile. In the given reaction the benzyl bromide…

Q: Enolates are formed by deprotonation of an α-carbon hydrogen. Answer the following questions about…

A: In this given molecule alpha carbon is adjacent carbon of carbonyl group, that is at the ring…

Q: Which of the following bases gives the highest Zaitsev product in an E2 reaction with…

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Q: Aniline reacts with bromine in the absence of a Lewis acid to give monosubstitution products. Draw a…

A: The aniline is a strong activating group even stronger than phenols, ethers, halogens, etc. This is…

Q: arrange the following alkyl bromides in order of decreasing reactivity in an SN1 reaction:…

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Q: Draw a reaction with reactant(s) and expected product(s) for each of the 6 alkyl halides  in the SN2…

A: The objective of the question is to predict the products of SN2 reactions involving six different…

Q: What is the intermediate product in the electrophilic aromatic substitution of benzene during…

A: Given reaction is aromatic electrophilic substitution reaction.

Q: Draw a reaction with reactant(s) and expected product(s) for each of the 6 alkyl halides  in the SN2…

A: The objective of the question is to predict the products of SN2 reactions involving six different…

Q: Which of the following is the best choice of reagent for the following transformation? OH Br OSOBr₂…

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Q: Predict the

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Q: True or false? 2-bromo-2-methylpropane undergoes SN1 rather than SN2 because the nucleophile…

A: Statement 01: 2-Bromo-2-methylpropane undergoes SN1 rather than SN2 because the nucleophile…

Q: Br (a) or II Br Br Br (b) or

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Q: Why do you think this was a major product of the reaction?  Did the above reaction followed an E1…

A: A question based on Hoffmann rule, which is to be accomplished.

Q: Each student must choose and analyze three of the four reactions: Rxn 1: Prop-1-yne reacts with H2…

A: 1. Alkyne reacts with hydrogen in the presence of palladium on a carbon catalyst to form an alkane.…

Q: Predict the starting alkyl bromide that would produce the product shown in the SN1 reaction. Assume…

A: In general, in SN1 mechanism, racemic mixture will be obtained , but here as there is no…

Q: Draw a reaction with reactant(s) and expected product(s) for each of the 6 alkyl halides  in the SN1…

A: SN1-  substitution Nucleophilic unimolecular.SN1 reaction proceeds via formation of carbocation.It…

Q: Consider the given alkyl halide reaction below. Which of the following statements is FALSE about the…

A: Alkyl halide gives solvolysis reaction water. The reaction proceeds by the SN1 mechanism and…

Q: Bromination of an alkene by N-bromosuccinimide (NBS) in the presence of light or peroxide is a…

A: The reaction given is,

Q: What is the purpose of CH3OH being the solvent? Isn't CH3S- the only reagent needed in order to go…

A: Here methanol act as solvent.  In substitution reaction solvent have two function.  1. Provide the…

Q: COOH COOH

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Q: an SN2/SN1 reaction occur

A: We know that the weaker base is a good leaving group. While strong base are poor leaving group.…

Q: Which of the following alkyl halides gives the slowest SN2 reaction? O 1-chloro ethane O…

A: Order of reactivity of alkyl halide in SN2 reaction is: 1° > 2° > 3° 1° alkyl halide are…

Q: Which solvent would make the bromination through electrophilic aromatic substitution faster?…

A: Generally bromination through electrophilic aromatic substitution is more efficient in polar…

Q: The oxygen in water is primarily (99.8%) 16O, but water enriched with the heavy isotope 18O is also…

A: When Aldehydes and ketones undergo addition of water, the carbonyl carbon forms gem-diols.The…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.