Draw a formula for Thr-Ala-Ala (T-A-A) in its predominant ionic form at pH 7.3. You may assume for the purposes of this question that the pKa values of the acidic groups ofamino acid residues in the peptide are the same as in the amino acid itself.O• You do not have to consider stereochemistry.• You do not have to explicitly draw H atoms.• Do not include lone pairs in your answer. They will not be considered in the grading.09.05- [ ]ChemDoodleⓇ Draw a formula for Ala-Gln-Asp (A-Q-D) in its predominant ionic form at pH 7.3. You may assume for the purposes of this question that the pKa values of the acidic groupsof amino acid residues in the peptide are the same as in the amino acid itself.• You do not have to consider stereochemistry.• You do not have to explicitly draw H atoms.• Do not include lone pairs in your answer. They will not be considered in the grading.=ChemDoodleⓇ

Here we are required to draw the structure of peptide predominant at pH 7.3

Draw a formula for Thr-Ala-Ala (T-A-A) in its predominant ionic form at pH 7.3. You may assume for the purposes of this question that the pKa values of the acidic groups of amino acid residues in the peptide are the same as in the amino acid itself. • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. 0.85 Po 24 On [F ChemDoodleⓇ

Draw a formula for Thr-Ala-Ala (T-A-A) in its predominant ionic form at pH 7.3. You may assume for the purposes of this question that the pKa values of the acidic groups of amino acid residues in the peptide are the same as in the amino acid itself. • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. 0.85 Po 24 On [F ChemDoodleⓇ

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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4. Proteases are enzymes that catalyze the hydrolysis of peptide bonds in proteins. The enzyme trypsin is a protease that specifically hydrolyzes only those peptide bonds that are formed by the carboxyl group of basic amino acid residues. Trypsin is present in the small intestine where it functions at an optimum pH of 8. Consider the pentapeptide Phe-His-Val-Lys-Glu. Draw the structures of the products formed from trypsin-catalyzed hydrolysis of this peptide.
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Refer to the bar graph below, Explain why the n→π* interactions contributes more to the overall stabilization of the protein than all the other interactions(C-H-O hydrogen bond,π-π interactions, C5 Hydrogen Bonds, Cation-π interactions, Sulfur-arene interactions, Anion-π interactions, Chalcogen bonds, X-H-π interactions) even though n→π* is the weaker interaction. Explain why that's the case for EACH of the bonds. I.e Why n→π* interactions contribute more to the overall stabilization of the protein than C-H-O hydrogen bonds, even though n→π* is the weaker interaction. Why n→π* interactions contribute more to the overall stabilization of the protein than π-π interactions even though n→π* is the weaker interaction. Why n→π* interactions contribute more to the overall stabilization of the protein than C5 Hydrogen Bonds, even though n→π* is the weaker interaction. Why n→π* interactions contribute more to the overall stabilization of the protein than Cation-π interactions, even though…
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