The R group of the amino acid Asp contains a carboxyl group with a pKa of 3.7. Bu the pka of the alpha-carboxyl group in Asp is 1.9. Which of the following. explanations could reasonably account for this difference? 3.7 is the isoelectric pH, which is estimated by averaging the pka of the alpha- carboxyl group with the much higher pKa of the alpha-amino group O The R group of Asp also contains an NH2 group, which is less acidic than a carboxylic acid The conjugate base of the alpha-carboxyl could be stabilized by an attractive ionic interaction with the nearby alpha-amino group, which is protonated at low pH Water has better access to the R group than to the alpha-carboxyl group, so it more effectively solvates the charged form of the R group and stabilizes it

The R group of the amino acid Asp contains a carboxyl group with a pKa of 3.7. Bu the pka of the alpha-carboxyl group in Asp is 1.9. Which of the following. explanations could reasonably account for this difference? 3.7 is the isoelectric pH, which is estimated by averaging the pka of the alpha- carboxyl group with the much higher pKa of the alpha-amino group O The R group of Asp also contains an NH2 group, which is less acidic than a carboxylic acid The conjugate base of the alpha-carboxyl could be stabilized by an attractive ionic interaction with the nearby alpha-amino group, which is protonated at low pH Water has better access to the R group than to the alpha-carboxyl group, so it more effectively solvates the charged form of the R group and stabilizes it

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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