Under the conditions of this extractive procedure, how does aspirin become partitioned into the aqueous layer? How do we then recover this substance in a pure form from the aqueous layer? The acidic hydrogen in the carboxyl group (-COOH) of aspirin undergoes an acid-base reaction O1) with NaOH to form the conjugate base, sodium 2-acetoxybenzoate. U 2) This ionic species then readily dissolves in water. 3) Conversely, the organic unknown does not possess an acidic residue, so no acid/base reaction can осcur. 4) It therefore does dissolye in water.

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Under the conditions of this extractive procedure, how does aspirin become partitioned into the aqueous layer? How
do we then recover this substance in a pure form from the aqueous layer?
O 1) The acidic hydrogen in the carboxyl group (-COOH) of aspirin undergoes an acid-base reaction
with NaOH to form the conjugate base, sodium 2-acetoxybenzoate.
U 2) This ionic species then readily dissolves in water.
3) Conversely, the organic unknown does not possess an acidic residue, so no acid/base reaction can
occur.
4) It therefore does dissolve in water.
Transcribed Image Text:Under the conditions of this extractive procedure, how does aspirin become partitioned into the aqueous layer? How do we then recover this substance in a pure form from the aqueous layer? O 1) The acidic hydrogen in the carboxyl group (-COOH) of aspirin undergoes an acid-base reaction with NaOH to form the conjugate base, sodium 2-acetoxybenzoate. U 2) This ionic species then readily dissolves in water. 3) Conversely, the organic unknown does not possess an acidic residue, so no acid/base reaction can occur. 4) It therefore does dissolve in water.
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