a. The chemical structures below show two analgesics (painkillers): acetaminophen and ibuprofen. Which analgesic would you expect to be more soluble in water at pH 7? Explain your answer by naming the intermolecular forces present in each molecule. CH3 CH3 LOH CH3 OH CH3 Acetaminophen Ibuprofen b. Imagine you wanted to increase acetaminophen's solubility in water. To what approximate pH would you adjust your solution of acetaminophen? What about if you wanted to increase the solubility of ibuprofen? Think about the pka's of the functional groups in each molecule.
a. The chemical structures below show two analgesics (painkillers): acetaminophen and ibuprofen. Which analgesic would you expect to be more soluble in water at pH 7? Explain your answer by naming the intermolecular forces present in each molecule. CH3 CH3 LOH CH3 OH CH3 Acetaminophen Ibuprofen b. Imagine you wanted to increase acetaminophen's solubility in water. To what approximate pH would you adjust your solution of acetaminophen? What about if you wanted to increase the solubility of ibuprofen? Think about the pka's of the functional groups in each molecule.
Chemistry: Principles and Reactions
8th Edition
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:William L. Masterton, Cecile N. Hurley
Chapter10: Solutions
Section: Chapter Questions
Problem 24QAP
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Question
![a. The chemical structures below show two analgesics (painkillers): acetaminophen
and ibuprofen. Which analgesic would you expect to be more soluble in water at pH 7?
Explain your answer by naming the intermolecular forces present in each molecule.
CH3
HO
N CH3
CH3
OH
CH3
Acetaminophen
Ibuprofen
b. Imagine you wanted to increase acetaminophen's solubility in water. To what
approximate pH would you adjust your solution of acetaminophen? What about if you
wanted to increase the solubility of ibuprofen? Think about the pka's of the functional
groups in each molecule.
В
I
Ff -
а.
b.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd556e803-222c-475e-bc6a-44d8250d1cd2%2F5c0e361a-c5d8-4d0a-94d5-f6025d476bef%2Fpfmkk2t_processed.png&w=3840&q=75)
Transcribed Image Text:a. The chemical structures below show two analgesics (painkillers): acetaminophen
and ibuprofen. Which analgesic would you expect to be more soluble in water at pH 7?
Explain your answer by naming the intermolecular forces present in each molecule.
CH3
HO
N CH3
CH3
OH
CH3
Acetaminophen
Ibuprofen
b. Imagine you wanted to increase acetaminophen's solubility in water. To what
approximate pH would you adjust your solution of acetaminophen? What about if you
wanted to increase the solubility of ibuprofen? Think about the pka's of the functional
groups in each molecule.
В
I
Ff -
а.
b.
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