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Determine the type of mutations based on the nucleotide change- indel vs substitution- that occurred in a sequence. Which of the following mutations would lead to a change in the reading frame in translation? Insertion of six Adenins Deletion of the start codon Insertion of CTA Deletion of two Cytocins

Determine the type of mutations based on the nucleotide change- indel vs substitution- that occurred in a sequence. Which of the following mutations would lead to a change in the reading frame in translation? Insertion of six Adenins Deletion of the start codon Insertion of CTA Deletion of two Cytocins

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Title: Understanding Mutations and Their Impact on Genetic Translation** **Introduction:** Mutations in DNA can lead to significant changes in genetic translation, affecting organismal traits. Key types of nucleotide changes include insertions and deletions (indels) and substitutions. Indels can cause shifts in the reading frame of mRNA during translation, potentially leading to altered protein synthesis. **Quiz Question:** Determine the type of mutations based on the nucleotide change—indel vs substitution—that occurred in a sequence. **Which of the following mutations would lead to a change in the reading frame in translation?** - ○ Insertion of six Adenines - ○ Deletion of the start codon - ○ Insertion of CTA - ○ Deletion of two Cytosines **Explanation:** Insertion or deletion of nucleotides not in multiples of three can disrupt the reading frame, causing a frameshift mutation. Such changes typically have significant impacts on protein function, leading to genetic disorders or variation. Analyzing these mutations helps understand genetic errors and develop corrective measures.
Transcribed Image Text:**Title: Understanding Mutations and Their Impact on Genetic Translation** **Introduction:** Mutations in DNA can lead to significant changes in genetic translation, affecting organismal traits. Key types of nucleotide changes include insertions and deletions (indels) and substitutions. Indels can cause shifts in the reading frame of mRNA during translation, potentially leading to altered protein synthesis. **Quiz Question:** Determine the type of mutations based on the nucleotide change—indel vs substitution—that occurred in a sequence. **Which of the following mutations would lead to a change in the reading frame in translation?** - ○ Insertion of six Adenines - ○ Deletion of the start codon - ○ Insertion of CTA - ○ Deletion of two Cytosines **Explanation:** Insertion or deletion of nucleotides not in multiples of three can disrupt the reading frame, causing a frameshift mutation. Such changes typically have significant impacts on protein function, leading to genetic disorders or variation. Analyzing these mutations helps understand genetic errors and develop corrective measures.
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