Need help with D and E on problem 6! **Problem 5:**Suppose a cell expresses HK-I and 5 mM is the concentration of glucose in the blood. Compare the cellular concentration of glucose (relative to 5 mM) based on the G6P concentration in the cell being low or high. **Problem 6:**Brain cells express HK-I and liver cells express HK-IV. This differential gene expression is an adaptation of cellular function to the blood glucose concentration, which averages 4-5 mM in a healthy body. Consider the specific conditions as shown in the figure.**Diagram Description:**The diagram illustrates two different types of cells and their respective enzymes and G6P concentrations:- A **brain cell** expresses HK-I and has low G6P concentration.- A **liver cell** expresses HK-IV and has low G6P concentration.Both cells are exposed to a blood glucose concentration of 5 mM.**Questions:****A.** In which cell is the rate of G6P formation greater? Justify your answer.**B.** Which cell has the higher rate of net glucose transport? Justify your answer.**C.** Give a reason to expect high G6P concentration in a cell with high energy charge.**D.** How would the rate of glucose transport into the liver cell change if the energy charge were to become low? Justify your answer.**E.** How would the rate of glucose transport into the brain cell change if the energy charge of the cell were to become high? Justify your answer.

Hexokinase or HK is an enzyme that is responsible for the phosphorylation of six-carbon or hexose…

D. How would the rate of glucose transport into the liver cell change if the energy charge were to become low? Justify your answer. E. How would the rate of glucose transport into the brain cell change if the energy charge of the cell were to become high? Justify your answer.

D. How would the rate of glucose transport into the liver cell change if the energy charge were to become low? Justify your answer. E. How would the rate of glucose transport into the brain cell change if the energy charge of the cell were to become high? Justify your answer.

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter6: Basic Clinical Chemistry

Section6.4: Point-of-care Testing

Problem 1RQ

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Immune Disorders

The collaboration between the cells and proteins that work together as a defense system against infection comprises the immune system.Each of them performs a variety of tasks to recognize and/or react against a foreign body.

Question

Need help with D and E on problem 6!

**Problem 5:**
Suppose a cell expresses HK-I and 5 mM is the concentration of glucose in the blood. Compare the cellular concentration of glucose (relative to 5 mM) based on the G6P concentration in the cell being low or high.

**Problem 6:**
Brain cells express HK-I and liver cells express HK-IV. This differential gene expression is an adaptation of cellular function to the blood glucose concentration, which averages 4-5 mM in a healthy body. Consider the specific conditions as shown in the figure.

**Diagram Description:**
The diagram illustrates two different types of cells and their respective enzymes and G6P concentrations:
- A **brain cell** expresses HK-I and has low G6P concentration.
- A **liver cell** expresses HK-IV and has low G6P concentration.

Both cells are exposed to a blood glucose concentration of 5 mM.

**Questions:**

**A.** In which cell is the rate of G6P formation greater? Justify your answer.

**B.** Which cell has the higher rate of net glucose transport? Justify your answer.

**C.** Give a reason to expect high G6P concentration in a cell with high energy charge.

**D.** How would the rate of glucose transport into the liver cell change if the energy charge were to become low? Justify your answer.

**E.** How would the rate of glucose transport into the brain cell change if the energy charge of the cell were to become high? Justify your answer.

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