Currently, studies are being done on whether one COVID vaccine (like Pfizer’s) can be mixed and matched with another COVID vaccine (like Moderna’s).  So a person could have the first shot of one and the second shot of the other.  Let’s say a study was done to try to determine if mixing and matching is as effective as just using one type for both shots.  People show up at a clinic on a Saturday (self-selecting), and are first given the Pfizer vaccine, and then the Moderna vaccine 3 weeks later.  Suppose the results showed that only 1% of all of the people got COVID.  What is a problem with this study? A) There was no random assignment of participants to groups. B) It is observational, and an experiment would have been better due to the potential of confounding. C) There was no control group, i.e. a group to compare the results to. D) All of the above

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Currently, studies are being done on whether one COVID vaccine (like Pfizer’s) can be mixed and matched with another COVID vaccine (like Moderna’s).  So a person could have the first shot of one and the second shot of the other.  Let’s say a study was done to try to determine if mixing and matching is as effective as just using one type for both shots.  People show up at a clinic on a Saturday (self-selecting), and are first given the Pfizer vaccine, and then the Moderna vaccine 3 weeks later.  Suppose the results showed that only 1% of all of the people got COVID.  What is a problem with this study?

  1. A) There was no random assignment of participants to groups.
  2. B) It is observational, and an experiment would have been better due to the potential of confounding.
  3. C) There was no control group, i.e. a group to compare the results to.
  4. D) All of the above

 

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Here, We have to discuss problem with this study one by one.

Definition:-

"A control group consists of a randomly assigned experimental units which does not take any experimental treatment(vaccine) and those are involved only for comparing results with those one who takes experimental treatment."

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