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Consider the hypothetical serine protease in the image, which shows the specificity pockets. The S1 pocket has a glutamic acid in the bottom, the S2 pocket is small and hydrophobic, and the S1' pocket is deep and hydrophobic. R3 Suggest a 3-amino acid sequence that this protease would cleave and indicate between which sites the peptide bond R would be broken. S2 Which sequence would this protease cleave? O Leu-Val-Arg Arg-Val-Leu Val-Leu-Arg Val-Arg-Leu Leu-Arg-Val Arg-Leu-Val

Consider the hypothetical serine protease in the image, which shows the specificity pockets. The S1 pocket has a glutamic acid in the bottom, the S2 pocket is small and hydrophobic, and the S1' pocket is deep and hydrophobic. R3 Suggest a 3-amino acid sequence that this protease would cleave and indicate between which sites the peptide bond R would be broken. S2 Which sequence would this protease cleave? O Leu-Val-Arg Arg-Val-Leu Val-Leu-Arg Val-Arg-Leu Leu-Arg-Val Arg-Leu-Val

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Attempt 8 Consider the hypothetical serine protease in the image, which shows the specificity pockets. The S1 pocket has a glutamic acid in the bottom, the S2 pocket is small and R3 H. R1 hydrophobic, and the S1' pocket is deep and hydrophobic. Suggest a 3-amino acid sequence that this protease would cleave and indicate between which sites the peptide bond R would be broken. S2 Si Which sequence would this protease cleave? O Leu-Val-Arg Arg-Val-Leu Val-Leu-Arg Val-Arg-Leu Leu-Arg-Val Arg-Leu-Val W Ma tv 894
Transcribed Image Text:Attempt 8 Consider the hypothetical serine protease in the image, which shows the specificity pockets. The S1 pocket has a glutamic acid in the bottom, the S2 pocket is small and R3 H. R1 hydrophobic, and the S1' pocket is deep and hydrophobic. Suggest a 3-amino acid sequence that this protease would cleave and indicate between which sites the peptide bond R would be broken. S2 Si Which sequence would this protease cleave? O Leu-Val-Arg Arg-Val-Leu Val-Leu-Arg Val-Arg-Leu Leu-Arg-Val Arg-Leu-Val W Ma tv 894
Leu-Val-Arg O Arg-Val-Leu Val-Leu-Arg Val-Arg-Leu O Leu-Arg-Val O Arg-Leu-Val The peptide bond that is broken is between which sites? S2 and S1, and S, and S,' S2 and S,' O S, and S1' S2 and S1
Transcribed Image Text:Leu-Val-Arg O Arg-Val-Leu Val-Leu-Arg Val-Arg-Leu O Leu-Arg-Val O Arg-Leu-Val The peptide bond that is broken is between which sites? S2 and S1, and S, and S,' S2 and S,' O S, and S1' S2 and S1
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