A. Observed genetic variation Substitution >1bp indel 1bp indel B. Mutation rate variation FIGURE 9.17 The rate of mutation surrounding nucleosomes is not constant. Substitution mutations peak in the nucleosomes themselves, and are at a low point in the linker regions. Conversely, insertion and deletion mutations (indel in the figure) are the opposite. Researchers are attempting to establish why this is. (From Semple, C. A, and Taylor, M. S. (2009). Molecular biology: The structure of change. Science 323, 347-348. Reprinted with permission from AAAS.) Frequency

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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On the basis of the information provided in Figure 9.17, complete the mechanisms for peptide-bond cleavage by (a) a cysteine protease, (b) an aspartyl protease, and (c) a metalloprotease.

A. Observed genetic variation
Substitution
>1bp indel
1bp indel
B. Mutation rate variation
FIGURE 9.17 The rate of mutation surrounding nucleosomes
is not constant. Substitution mutations peak in the nucleosomes
themselves, and are at a low point in the linker regions. Conversely,
insertion and deletion mutations (indel in the figure) are the opposite.
Researchers are attempting to establish why this is. (From Semple, C. A,
and Taylor, M. S. (2009). Molecular biology: The structure of change.
Science 323, 347-348. Reprinted with permission from AAAS.)
Frequency
Transcribed Image Text:A. Observed genetic variation Substitution >1bp indel 1bp indel B. Mutation rate variation FIGURE 9.17 The rate of mutation surrounding nucleosomes is not constant. Substitution mutations peak in the nucleosomes themselves, and are at a low point in the linker regions. Conversely, insertion and deletion mutations (indel in the figure) are the opposite. Researchers are attempting to establish why this is. (From Semple, C. A, and Taylor, M. S. (2009). Molecular biology: The structure of change. Science 323, 347-348. Reprinted with permission from AAAS.) Frequency
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