Consider the cigarette smoke contain an average of 450 ppm carbon monoxide. If the average oxygen content in the air in the lungs is 19%, what percentage of the saturation level would the COHb concentration ultimately reach? Please provide the calculation
Consider the cigarette smoke contain an average of 450 ppm carbon monoxide. If the average oxygen content in the air in the lungs is 19%, what percentage of the saturation level would the COHb concentration ultimately reach? Please provide the calculation
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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Consider the cigarette smoke contain an average of 450 ppm carbon monoxide. If the average oxygen content in the air in the lungs is 19%, what percentage of the saturation level would the COHb concentration ultimately reach?
Please provide the calculation
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Step 1: determine the maximum capacity of hemoglobin to bind with carbon monoxide (CO).
VIEWStep 2: Calculate the partial pressure of CO (PPCO) using the given concentration of CO in cigarette smoke,
VIEWStep 3: Use the dissociation constant (Kd) for CO binding to hemoglobin, which is approximately 210 mmHg at
VIEWStep 4: Calculate the percentage of hemoglobin bound to CO
VIEWStep 5: Convert ppm to mmHg (1 ppm ≈ 0.12 mmHg):
VIEWStep 6: Calculate the numerator and denominator:
VIEWStep 7: Calculate the percentage: C O H b S a t u r a t i o n ( % ) = 20.45 % COHbSaturation(%)=20.45
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