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Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation n the gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele s notated as Cnorm, and the mutant allele is notated as Cmut. Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X -hromosome and Cnorm on the Y chromosome (XCmutyCnorm). Select all possible genotypes of their offspring for females. XCnorm Cmut XCnormx Cnorm XCmutxCmut Select all possible genotypes of their offspring for males. XCnormyCnorm XCmuty Cnorm XCmuty Cmut XCnormyCmut Which genotype is associated with the disease phenotype for pulmonary alveolar proteinosis? O None of these.

Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation n the gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele s notated as Cnorm, and the mutant allele is notated as Cmut. Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X -hromosome and Cnorm on the Y chromosome (XCmutyCnorm). Select all possible genotypes of their offspring for females. XCnorm Cmut XCnormx Cnorm XCmutxCmut Select all possible genotypes of their offspring for males. XCnormyCnorm XCmuty Cnorm XCmuty Cmut XCnormyCmut Which genotype is associated with the disease phenotype for pulmonary alveolar proteinosis? O None of these.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation in the gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele is notated as Cnorm, and the mutant allele is notated as Cmut. Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X chromosome and Cnorm on the Y chromosome (XCmutyCnorm). Select all possible genotypes of their offspring for females. XCnormx Cmut XCnormy Cnorm XCmutxC Cmut Which genotype is associated with the disease phenotype for pulmonary alveolar proteinosis? None of these. Select all possible genotypes of their offspring for males. XCnormyCnorm XCmuty Cnorm XCmuty Cmut XCnormyCmut O XCnormyCmut XCnormYCmut O XCmutYCnorm
Transcribed Image Text:Congenital pulmonary alveolar proteinosis is a rare lung disease in humans. The disease is caused by a recessive mutation in the gene CSF2RA. CSF2RA is located within a pseudoautosomal region of the X and Y chromosomes. The normal allele is notated as Cnorm, and the mutant allele is notated as Cmut. Suppose that a woman with Cnorm on both X chromosomes (XCnormyCnorm) has children with a man with Cmut on the X chromosome and Cnorm on the Y chromosome (XCmutyCnorm). Select all possible genotypes of their offspring for females. XCnormx Cmut XCnormy Cnorm XCmutxC Cmut Which genotype is associated with the disease phenotype for pulmonary alveolar proteinosis? None of these. Select all possible genotypes of their offspring for males. XCnormyCnorm XCmuty Cnorm XCmuty Cmut XCnormyCmut O XCnormyCmut XCnormYCmut O XCmutYCnorm
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