Conditions: [Na+] outside = .3 mM [Na+] inside the presynaptic cell = .01 mM [dopamine] inside = .5 mM [dopamine] outside = .001 mM ΔGinward = RT ln [X] inside/[X] outside + z F Vm F = 23,000 cal/mol V R = 1.987 cal/ mol K Membrane potential is .07 V Temperature is 273 K Using the attachment the information provided, please answer the following questions : Using what you know about transport across membranes, would the movement of sodium INTO the cell be active or passive? SHOW your work.
Conditions:
[Na+] outside = .3 mM
[Na+] inside the presynaptic cell = .01 mM
[dopamine] inside = .5 mM
[dopamine] outside = .001 mM
ΔGinward = RT ln [X] inside/[X] outside + z F Vm
F = 23,000 cal/mol V
R = 1.987 cal/ mol K
Membrane potential is .07 V
Temperature is 273 K
Using the attachment the information provided, please answer the following questions :
- Using what you know about transport across membranes, would the movement of sodium INTO the cell be active or passive? SHOW your work.
2. Using all of this information, how could you explain how dopamine can re-enter the presynaptic cell – i.e. where does the energy come from? Use the information in this question to formulate your answer.
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