Complete the road map problem shown below by drawing the product of each step of the reaction sequence in the boxes. NaOEt OH H CI cat. H* H*/H2O PBR3 ОН
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![**Title: Reaction Road Map Problem**
**Description:**
Complete the road map problem shown below by drawing the product of each step of the reaction sequence in the boxes.
**Reaction Scheme:**
1. **Reactants:**
\[
\begin{array}{cc}
\begin{array}{c}
O \\
|| \\
H-C-CH_2-CH_2-C-Cl \\
|| \\
O
\end{array}
& \xrightarrow{\text{NaOEt}}
\end{array}
\]
2. **First Reaction Product:**
\[(first box: Draw the product here)\]
3. **Second Reaction:**
\[\text{HO-CH2-CH2-OH, cat. H+} \rightarrow\]
4. **Second Reaction Product:**
\[(second box: Draw the product here)\]
5. **Third Reaction:**
\[\downarrow\]
6. **Third Reaction Product:**
\[(third box: Draw the product here)\]
7. **Reactants for Fourth Reaction:**
\[
\begin{array}{cc}
\begin{array}{c}
PBr_3 \\
\rightarrow
\end{array}
& \begin{array}{c}
H^+/H_2O \\
\leftarrow
\end{array}
\end{array}
\]
8. **Final Product:**
\[
\begin{array}{c}
\begin{array}{c}
\begin{array}{c}
\text{(pentagon shape, oxygen at one corner with an oxygen going to another pentagon)} \\
-CH_2-CH_2-CH_2-C-CH_3\_ \text{- 2 CH3 attached to the CH}
\end{array}
-1 CH2 attached to the carbon (CH2)
\end{array}
-OH
\end{array}
\]
The final product is a pentagonally shaped, contains two oxygen atoms, and hydroxyl (OH) group attached to the third carbon in the pentagon.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F30c2e2f2-e45c-41de-86ef-a25e36084e76%2F5ea5ead9-02fe-4997-ac9d-56520a897484%2F5mtlw2.jpeg&w=3840&q=75)
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