HBr KCN DMSO B 1. CH₂MgBr, diethyl ether 2. H₂O+

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Complete the synthesis below by drawing the structure of the organic product in each step. Draw the structure of A, B and C.
**Chemical Reaction Sequence**

This diagram illustrates a three-step chemical reaction sequence starting with a cyclic alkene, proceeding through various reagents, and yielding product C.

1. **Step 1:**
   - **Reactant:** Cyclohexene
   - **Reagent:** Hydrobromic acid (HBr)
   - **Product A:** An intermediate product is formed after the addition of HBr to the cyclohexene.

2. **Step 2:**
   - **Reagent:** Potassium cyanide (KCN)
   - **Solvent:** Dimethyl sulfoxide (DMSO)
   - **Transformation:** The intermediate A undergoes substitution with KCN in the presence of DMSO to form product B.

3. **Step 3:**
   - **Reagents:**
     1. Methylmagnesium bromide (CH₃MgBr) in diethyl ether
     2. Acidic workup with H₃O⁺
   - **Outcome:** The intermediate B is further reacted with a Grignard reagent in an ether solvent, followed by an acidic workup to yield final product C.

Each step represents a transformation in organic chemistry, involving typical reagents and solvents used for such processes.
Transcribed Image Text:**Chemical Reaction Sequence** This diagram illustrates a three-step chemical reaction sequence starting with a cyclic alkene, proceeding through various reagents, and yielding product C. 1. **Step 1:** - **Reactant:** Cyclohexene - **Reagent:** Hydrobromic acid (HBr) - **Product A:** An intermediate product is formed after the addition of HBr to the cyclohexene. 2. **Step 2:** - **Reagent:** Potassium cyanide (KCN) - **Solvent:** Dimethyl sulfoxide (DMSO) - **Transformation:** The intermediate A undergoes substitution with KCN in the presence of DMSO to form product B. 3. **Step 3:** - **Reagents:** 1. Methylmagnesium bromide (CH₃MgBr) in diethyl ether 2. Acidic workup with H₃O⁺ - **Outcome:** The intermediate B is further reacted with a Grignard reagent in an ether solvent, followed by an acidic workup to yield final product C. Each step represents a transformation in organic chemistry, involving typical reagents and solvents used for such processes.
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