Compare the regulation of the pyruvate dehydrogenase complex in muscle and in liver.

Q: The pyruvate dehydrogenase (PDH) complex catalyzes the oxidative decarboxylation of pyruvate to…

A: Pyruvate dehydrogenase (PDH) complex oxidizes pyruvate to acetyl-CoA and carbon dioxide. It takes…

Q: Describe how pyruvate concentration in the matrix of the mitochondria increases based on the glucose…

A: The process of breakdown of glucose to yield two molecules each of pyruvate, ATP (adenosine…

Q: ist the inhibitors and activators of the Pyruvate Dehydrogenase Complex observed in most species?

A: Pyruvate dehydrogenase (PDH) complex is a multi-enzyme complex and catalyzes conversion of pyruvate…

Q: Which of the enzymes in glycolysis are NADH linked dehydrogenases?

A: Glycolysis is the first step in energy production from glucose. Carbohydrates from the food are…

Q: Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? more…

A: The objective of the question is to identify the enzymes that are affected by the elevated levels of…

Q: Please explain how glycolysis is linked to the CAC.

A: CAC : Citric acid cycle  Pyruvate : Glycolysis end product  Glycolysis, the CAC are linked via the…

Q: After the transamination, write out the subsequent steps (no mechanisms) to fully oxidize aspartate…

A: Transamination is a chemical process in which an amino group is transferred to a ketoacid, resulting…

Q: After several days of starvation, the ability of the liver to metabolize acetyl-CoA via the citric…

A: During starvation, glycogen stored as a fuel is used up by the liver to supply the required amount…

Q: Explain why inhibiting the activity of acetyl-CoA carboxylase might not affect a person’s body mass.

A: Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme that catalyzes the irreversible…

Q: glucose oxidative pathways

A: Glucose is completely oxidized after chemiosmosis because that's when the final products of…

Q: Most defects in pyruvate dehydrogenase complex are due to mutations in ______, so supplements with…

A: Introduction  Pyruvate dehydrogenase is a complex of enzymes that plays a critical role in aerobic…

Q: Which precursors accumulate in patients with niacin deficiency. What effect does this deficiency…

A: Niacin is a precursor to nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine…

Q: Pyruvate can enter the TCA cycle via two enzymatic reactions. Provide a simplified schematic…

A:

Q: Pyruvate dehydrogenase can be activated by

A: Introduction Pyruvate dehydrogenase(PDH) is an enzyme complex of three individual enzymes along with…

Q: Discuss regulation of glycolysis and the citric acid cycle, including likely activators and…

A: 3 enzymes of glycolysis are regulated . They are; Hexokinase, Phosphofructokinase-1 (PFK-1) and…

Q: Describe the advantage of regenerating oxaloacetate at the end of each turn of the citric acid…

A: ATP is the energy currency for all living cells. The citric acid cycle is also known as the…

Q: Describe two different ways in which glucose oxidase is regulated.

A: Answer: - Glucose oxidase is a subset of oxidoreductase compounds that catalyzes the exchange of…

Q: In the fasted state, FADH2 and NADH for oxidative phosphorylation are mainly provided by fatty acid…

A: Fatty acid oxidation is a process by which fatty acids are broken down and used as energy. It is…

Q: Distinguish between catalytic coenzymes and stoichiometric coenzymes in the pyruvate dehydrogenase…

A: The Pyruvate dehydrogenase complex consists of five different coenzymes such as thiamine…

Q: Explain How arsenic affects the pyruvate dehydrogenase reaction

A: Pyruvate dehydrogenase reaction is a reaction in which pyruvate is converted into acetyl-CoA.

Q: What is the physiologic significance of pyruvate dehydrogenase complex?What's the biochemical basis…

A: Hi! As you have asked multiple questions, we are answering only the first two for you. If you need…

Q: Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? Pyruvate…

A: Acetyl-CoA is a very essential molecule in the cellular metabolism. It serves as a central player in…

Q: Describe the movement of energy during acetyl–CoA formationand the citric acid cycle.

A: It takes acetyl CoA start text, C, o, A, end text—produced by the oxidation of pyruvate and…

Q: The citric acid cycle is mainly controlled at the first two NADH-producing reactions catalyzed by…

A: Citric acid cycle is the second stage of cellular respiration during which Acetyl CoA is reduced to…

Q: A patient exhibiting all the symptoms of beriberi is placed on a thiamine-enriched diet; however,…

A: Beriberi is a nutritional deficiency disorder that causes debilitating neurologic symptoms and…

Q: Describe the mechanism for moving acetyl-CoA produced in the mitochondrial matrix into the cytosol…

A: An enzyme called acetyl CoA carboxylase in the cytoplasm catalyzes the carboxylation of Acetyl CoA…

Q: How does pyruvate from glycolysis get to the pyruvate dehydrogenase complex?

A: Pyruvate dehydrogenase complex : It is a complex of three enzymes that converts pyruvate into…

Q: xplain the indirect effect that allosteric effectors have on pyruvate dehydrogenase activity through…

A: The pyruvate dehydrogenase complex acts a a connection between glycolysis, the tricarboxylic acid…

Q: Discuss the connection between glycolysis and the oxidative pentose phosphate pathway.

A: Glycolysis is a metabolic pathway during which glucose molecule splits into pyruvate molecules with…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.