Compare the regulation of the pyruvate dehydrogenase complex in muscle and in liver.

Q: The pyruvate dehydrogenase (PDH) complex catalyzes the oxidative decarboxylation of pyruvate to…

A: Pyruvate dehydrogenase (PDH) complex oxidizes pyruvate to acetyl-CoA and carbon dioxide. It takes…

Q: Describe how pyruvate concentration in the matrix of the mitochondria increases based on the glucose…

A: The process of breakdown of glucose to yield two molecules each of pyruvate, ATP (adenosine…

Q: Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? more…

A: The objective of the question is to identify the enzymes that are affected by the elevated levels of…

Q: Please explain how glycolysis is linked to the CAC.

A: CAC : Citric acid cycle  Pyruvate : Glycolysis end product  Glycolysis, the CAC are linked via the…

Q: After the transamination, write out the subsequent steps (no mechanisms) to fully oxidize aspartate…

A: Transamination is a chemical process in which an amino group is transferred to a ketoacid, resulting…

Q: Most defects in pyruvate dehydrogenase complex are due to mutations in ______, so supplements with…

A: Introduction  Pyruvate dehydrogenase is a complex of enzymes that plays a critical role in aerobic…

Q: Which precursors accumulate in patients with niacin deficiency. What effect does this deficiency…

A: Niacin is a precursor to nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine…

Q: Discuss regulation of glycolysis and the citric acid cycle, including likely activators and…

A: 3 enzymes of glycolysis are regulated . They are; Hexokinase, Phosphofructokinase-1 (PFK-1) and…

Q: Describe two different ways in which glucose oxidase is regulated.

A: Answer: - Glucose oxidase is a subset of oxidoreductase compounds that catalyzes the exchange of…

Q: In the fasted state, FADH2 and NADH for oxidative phosphorylation are mainly provided by fatty acid…

A: Fatty acid oxidation is a process by which fatty acids are broken down and used as energy. It is…

Q: Explain How arsenic affects the pyruvate dehydrogenase reaction

A: Pyruvate dehydrogenase reaction is a reaction in which pyruvate is converted into acetyl-CoA.

Q: What is the physiologic significance of pyruvate dehydrogenase complex?What's the biochemical basis…

A: Hi! As you have asked multiple questions, we are answering only the first two for you. If you need…

Q: Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? Pyruvate…

A: Acetyl-CoA is a very essential molecule in the cellular metabolism. It serves as a central player in…

Q: A patient exhibiting all the symptoms of beriberi is placed on a thiamine-enriched diet; however,…

A: Beriberi is a nutritional deficiency disorder that causes debilitating neurologic symptoms and…

Q: Describe the mechanism for moving acetyl-CoA produced in the mitochondrial matrix into the cytosol…

A: An enzyme called acetyl CoA carboxylase in the cytoplasm catalyzes the carboxylation of Acetyl CoA…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.