Compare the pathways of purine and pyrimidine nucleotide synthesis with respect to (a) precursors, (b) energy cost, (c) acquisition of the ribose moiety, and (d) number of enzymatic steps.

Q: Explain why methotrexate inhibits the synthesis of histidine and methionine.

A: Competitive inhibition is the competition between a substrate and inhibitor that compete for the…

Q: What peptides are expected to be produced when α-melanotropin is cleaved by (a) trypsin, (b)…

A: Protein is a polymer of amino acids connected together via a peptide bond. It may have one or…

Q: Lactose--->galactose+glucose represents an enzymatic reaction. What statement about this reaction is…

A: Lactase, also known as lactase-phlorizin hydrolase, is an enzyme found in animals' small intestine…

Q: The antibiotic cordycepin inhibits bacterial RNA synthesis. Solve, (a) Of which nucleoside is…

A: Cordycepin is an antibiotic, which also acts as an anti-inflammatory compound as well as…

Q: The effect of ATP on the allosteric enzyme PFK-1 is shown below. For a given concentration of…

A: Introduction  Enzymes with an extra binding site for effector molecules outside of the active site…

Q: Classify the following enzymes: Oxidoreductase, Hydrolase, Transferase, Lyase, Ligase, Isomerase 1.…

A: Introduction: Enzymes are biological catalysts that mean catalysts of life. They are protein by…

Q: Construct the mechanism of a serine-protease with a catalytic triad.

A: A serine protease is an enzyme that cleaves peptide bonds in proteins and peptides. It possesses a…

Q: Consider the peptide Asp-Lys-Phe-Glu-Asn-Tyr-Gln-Val-Cys. In a single beaker, you treat this peptide…

A: The amino acids that form peptide chains can be either polar/non-polar, charged/uncharged,…

Q: How many NTP molecules are required to synthesize glucose from each of the following compounds? (a)…

A: Introduction: Gluconeogenesis is a metabolic pathway that creates glucose from carbon substrates…

Q: 1. Which of the following enzymes can polymerize deoxyribonucleotides into DNA? A) Primase B) DNA…

A: There are different biomolecules present, and they include nucleic acids, proteins, lipids,…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.