Choose the electrolyte that you think is the most critical to maintain, i.e., the most significant electrolyte that is regulated by the kidneys to maintain normal body function.  Indicate where in the nephron (PCT, Loop, DCT) this electrolyte is regulated (appropriate amounts returned to the blood). Determine if an under-regulated (a hyper- condition) or an over-regulated (a hypo- condition) is the most critical of the electrolyte you've chosen that would life threatening.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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During the study on Fluids, Electrolytes and Acid-Base Balance (Ch 26), we've looked at respiratory and renal acidosis/alkalosis concerns.  The amount of CO2 and HCO3- in the blood triggers mechanisms to help balance blood pH so that the environment for normal biochemical reactions taking place in the body is present.  The use of buffers helps to make sure that the body's environment is just right so that all internal functions are working. The kidneys do much more than help regulate the amount of CO2 and bicarbonate in the body.  The Removal and Regulation functions of the kidneys includes electrolyte balance to make sure all organ systems can function. Below is a list of electrolytes regulated by the kidneys: Sodium - Na+ Potassium - K+ Phosphate - PO43- Chloride - Cl- Calcium - Ca2+ Magnesium- Mg2+ Conditions of excessive amounts or too little amounts create abnormalities.  Some of these abnormalities (hyper- or hypo- conditions) can be life threatening.   Directions for the Discussion: Choose the electrolyte that you think is the most critical to maintain, i.e., the most significant electrolyte that is regulated by the kidneys to maintain normal body function.  Indicate where in the nephron (PCT, Loop, DCT) this electrolyte is regulated (appropriate amounts returned to the blood). Determine if an under-regulated (a hyper- condition) or an over-regulated (a hypo- condition) is the most critical of the electrolyte you've chosen that would life threatening.  List the correct name of the condition associated with the electrolyte. Explain why you feel this electrolyte condition is the most critical.  Your explanation should include the organ system most affected by either the under- or over-regulated electrolyte.  You may also want to include conditions or other organ system dysfunctions that could result from your chosen electrolyte condition that contributes to the life threatening situation.  A little research and review of all systems covered in Anatomy & Physiology may help you explain your choice.
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