CHOICES: Physical Agent Base Analogs Alkylating Agent Intercalating Agent Metal ions Biological Agent Disrupt DNA structures and can cause frameshift mutation Denatures DNA and causes breakage or cleavage of the phosphodiester bonds through heat Induces the base-pairing errors that increases the ionization and production of gaps in the strand of the DNA. Producing ROS (reactive oxygen species), hindering the DNA repair pathway. Non-coding DNA sequences, jumps from one place to another place in a genome and influence the function of genes. Ethylnitrosourea Causes cross-linking and generation of nucleotide dimers. Able to hotwire our DNA make up and cause disease by expressing genes that causes abnormal production of proteins. Fe2+ Daunorubicin 2-Aminopurine Arsenic Able to pair with adenine and is able to produces mutation. Thio-TEPA
Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
CHOICES:
|
Physical Agent |
|
Base Analogs |
|
Alkylating Agent |
|
Intercalating Agent |
|
Metal ions |
|
Biological Agent |
- Disrupt DNA structures and can cause frameshift mutation
- Denatures DNA and causes breakage or cleavage of the phosphodiester bonds through heat
- Induces the base-pairing errors that increases the ionization and production of gaps in the strand of the DNA.
- Producing ROS (reactive oxygen species), hindering the DNA repair pathway.
- Non-coding DNA sequences, jumps from one place to another place in a genome and influence the function of genes.
- Ethylnitrosourea
- Causes cross-linking and generation of
nucleotide dimers. - Able to hotwire our DNA make up and cause disease by expressing genes that causes abnormal production of proteins.
- Fe2+
- Daunorubicin
- 2-Aminopurine
- Arsenic
- Able to pair with adenine and is able to produces mutation.
- Thio-TEPA
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