Do question 40 Which of the following is false regarding DNA repair mechanisms?DNA ligase is needed to establish phosphodiester bonds after nucleotide excision repair,mismatch repair and base excision repairThymine dimers are repaired by nucleotide excision repair enzymesTransition mutations, whereby a purine is changed to a purine, or a pyrimidine is changed toa pyrimidine are the most common mutations made by DNA polymerasesMismatch repair enzymes excise and replace only the single nucleotide that needs to bereplacedBase excision repair enzymes remove and replace uracil bases that occur as a result ofdeamination

DNA repair is a process by which a cell identifies and corrects damage to the DNA molecules. Most…

Answered: Which of the following is false…

Which of the following is false regarding DNA repair mechanisms? DNA ligase is needed to establish phosphodiester bonds after nucleotide excision repair mismatch repair and base excision repair

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter9: Molecular Biology

Section: Chapter Questions

Problem 5RQ: The initial mechanism for repairing nucleotide errors in DNA is _____. a. mismatch repair b. DNA...

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Question

Do question 40

Which of the following is false regarding DNA repair mechanisms?
DNA ligase is needed to establish phosphodiester bonds after nucleotide excision repair,
mismatch repair and base excision repair
Thymine dimers are repaired by nucleotide excision repair enzymes
Transition mutations, whereby a purine is changed to a purine, or a pyrimidine is changed to
a pyrimidine are the most common mutations made by DNA polymerases
Mismatch repair enzymes excise and replace only the single nucleotide that needs to be
replaced
Base excision repair enzymes remove and replace uracil bases that occur as a result of
deamination

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Match the bold DNA repair response(s) to the triggering type of DNA damage. Homologous Recombination Mishmatch Repair Base Excision Repair Nucleotide Excision Repair Non-homologous End Joining Single-strand DNA breaks Removal of repair lesions such as photoproducts caused by UV including Thymine dimers Double-Strand Break repair mechanism which is an accurate repair mechanism without any introduction of insertions or deletions. It requires a sister chromatid as a template. This repair mechanism uses just DNA glycosylase to remove Uracil (no other enzymes or complexes are required) then DNA polymerase can use the template stand to add the complementary base where the Uracil has been removedInterstrand Crosslink Repair This repair mechanism is used to recognize and repair mis-incorporation of base that can arise during DNA replication. Removal and replacement of modifying bases such as Uracil, 8-hyroxyguanine and others. Double-strand Break that is termed as “Quick and Dirty” as it is…
Which of the following DNA repair processes is known to be "error-prone" (i.e. resulting in incorporation of incorrect nucleotides as part of the repair process)? Mark all the answers that are correct. Base Excision Repair (BER) non-homologous end-joining of double-stranded DNA breaks. O Nucleotide Excision Repair (NER) post-replication repair SO-response
Which of the following DNA repair processes is known to be "error-prone" (i.e. resulting in incorporation of incorrect nucleotides as part of the repair process)? Mark all the answers that are correct. post-replication repair Nucleotide Excision Repair (NER) M non-homologous end-joining of double-stranded DNA breaks. SOS-response O Base Excision Repair (BER)
Match the DNA repair mechanism to the type of repair it fixes. Base excision repair DNA polymerase proofreading Non-homolgous end-joining Mismatch repair Nucleotide excision repair Double strand breaks Mismatches in S-phase Mismatches after S-phase, before M-phase Mismatches in interphase Thymidine Dimer Double strand breaks Mismatches in S-phase Mismatches after S-phase, before…
Which of the following is correct about the function of DNA Ligase? DNA ligase is used on the leading strand and it joins any disconnected strand together O DNA ligase is used on the lagging strand which helps in joining fragments of the strand together O DNA ligase is used on the lagging strand and it aids in correcting mistakes on this specific strand O DNA ligase is used to maintain the replication fork structure
Which of the following statements regarding Nucleotide Excision Repair (NER) and Base Excision Repair (BER) is true? Only NER involves the action of DNA ligase to seal nicks in the DNA backbone. Both NER and BER involve DNA strand cleavage by an endonuclease. Both NER and BER can be activated by exposure to visible light. Only BER requires DNA polymerase. Both NER and BER involve the creation of an apyrimidinic (AP) site.
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Which of the following statements regarding Nucleotide Excision Repair (NER) and Base Excision Repair (BER) is true? Only NER involves the action of DNA ligase to seal nicks in the DNA backbone. Both NER and BER involve the creation of an apyrimidinic (AP) site. Both NER and BER involve a single DNA strand cleavage by an endonuclease. Only BER requires DNA polymerase. Both NER and BER can be activated by exposure to visible light.
Which of the following DNA repair mechanisms involves the 3' to 5' exonuciease function of DNA polymerase? mismatch repair postreplication repair SOS response DNA proofreading base excision repair
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Among the different types of DNA repair, one has the unique ability to detect which strand is the newly synthesized strand where DNA polymerase may have mis-incorporated a base. This repair is Group of answer choices Photolyase Nucleotide excision repair Base excision repair SOS repair Mismatch Repair
Which of the following statements is TRUE? Synthesis of the lagging strand requires more DNA helicase enzymes than synthesis of the leading strand. The lagging strand is synthesized in a semiconservative fashion while the leading strand is synthesized in a conservative fashion. The leading strand is replicated continuously for the entire length of the chromosome, e.g. while the lagging strand has multiple origins of replication The lagging strand has a higher mutation rate than the leading strand. None of the answers are true.