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Chapter : Lipid Metabolism "It has been proposed that malonyl CoA may be one of the signals sent to the brain to decrease the appetite response. When mice are given a derivative of cerulenin (a fungal epoxide) named C75, their appetite is suppressed and they rapidly lose weight. Cerulenin and its derivatives have been shown to be potent inhibitors of fatty acid synthase (FAS). Suggest how C75 might act as a potential weight reduction drug" Thanks. Please write the answers clearly.

Chapter : Lipid Metabolism "It has been proposed that malonyl CoA may be one of the signals sent to the brain to decrease the appetite response. When mice are given a derivative of cerulenin (a fungal epoxide) named C75, their appetite is suppressed and they rapidly lose weight. Cerulenin and its derivatives have been shown to be potent inhibitors of fatty acid synthase (FAS). Suggest how C75 might act as a potential weight reduction drug" Thanks. Please write the answers clearly.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Chapter : Lipid Metabolism

"It has been proposed that malonyl CoA may be one of the signals sent to the brain to decrease the appetite response. When mice are given a derivative of cerulenin (a fungal epoxide) named C75, their appetite is suppressed and they rapidly lose weight. Cerulenin and its derivatives have been shown to be potent inhibitors of fatty acid synthase (FAS). Suggest how C75 might act as a potential weight reduction drug"

Thanks. Please write the answers clearly.

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