CHALLENGE QUESTION I: Smurf hemoglobin has a p50 of 30 torr and has 8 subunits, instead of the usual 4. It binds O2 with perfect positive cooperativity. What is the fractional saturation of Smurf hemoglobin at poz-37 torr (the partial pressure on top of Smurf mountain)?
Q: Arrange the following FAs in decreasing melting point. * A. A 22-carbon series saturated FA B. An…
A: Melting point of Fatty acids depend upon several factors like Molecular weight Degree of Saturation…
Q: In the 1step of the 2-step reaction shown below, which substrate/co-substrate is being oxidized?…
A: The above reaction is a part of beta oxidation of fatty acid process.
Q: Compare the net production of ATP from four molecules of glucose (4 x C6) with that from one…
A: Glucose is oxidized through glycolysis, pyruvate dehydrogenase reaction, and the TCA cycle into…
Q: a. Name the phosphoinositide generated through the action of PI-5 kinase. b. Name the products…
A: Phosphatidylinositol (PI)-related signalling is important for survival, cell proliferation,…
Q: A man just ate a plant-based hamburger with a bun and nothing else on the sandwich.Coincidentally,…
A: As man ate plant-based hamburger with a bun. Plant based hamburger is made up basically from…
Q: All the dehydrogenases of glycolysis and the citric acid cycle use NAD+ (E°' for NAD+/NADH is -0.32…
A: NADH/FADH2 are also known as reducing equivalents. These reducing equivalents are produced in the…
Q: Which of the following statements are TRUE? Multiple answers:Multiple answers are accepted for…
A: In given Questions many statement given about glycolysis cycle.Glycolysis is the metabolic pathway…
Q: Using linear regression analysis, determine the values of Vmax and Km of the enzyme in the ab- sence…
A: Enzymes are highly specialized proteins that have extraordinary catalytic power, greater than that…
Q: What are examples of enzymes?
A: Enzymes are nothing but Proteins that help us in our metabolic pathways to increase the rate of…
Q: H3C H3C. HyC O Triglyceride O Fatty acid Glycerol
A: Fatty acids are important micromolecules which combine together to form lipids in plants, animals…
Q: Explain the biochemical consequences of ADA deficiency and explain them using the purine degradation…
A: The purine nucleotides are sequentially degraded by the removal of portions of nucleotides. The…
Q: Which of the following is NOT a primary method used to regulate the activity of cyclin-dependent…
A: Cyclin-dependent kinases (CDKs) are the protein kinases which plays a role in regulating the cell…
Q: Some of the mammalian Hox genes have been shown tobe more similar to one of the insect Hox genes…
A: The Hox genes are a group of transcription factor genes that have a unique property: they all have…
Q: Two peptide sequences are shown below. Peptide A: N-term – GDL – C-term Peptide B: N-term – GTL –…
A: A peptide is a short chain of amino acids that contains one or more amino acids. Peptide bonds…
Q: 1. What are the three major pathways that eventually become entry points of molecules into the Krebs…
A: Hi! Thank you for the question, as per the honor code, we are allowed to answer the first…
Q: List the key challenges in the biosynthesis phosphatidylcholine.
A: The most common PL identified in circulating VLDL is phosphatidylcholine (PC) . PC is produced in…
Q: Only eukaryotic transcription enzymes will synthesize small nuclear RNA molecules involved in the…
A: Small nuclear RNA (snRNA) are a class of small RNA molecules. They are found within the splicing…
Q: Suggest, which enzyme pathway come into play
A: Phenylalanine is an aromatic and non-polar amino acid, it is both glucogenic (Fumarate) and…
Q: List the three (3) types of RNA molecules and in one sentence each describe their functions.
A: RNA is Ribo Nucleic acid which is also one of the essential biomolecules essential for life. It is…
Q: Which of the following statements are FALSE? Multiple answers:Multiple answers are accepted for…
A: Which of the following statements are FALSE? Multiple answers:Multiple answers are…
Q: 2) a. Give the name of the following glycoside: но. он но но b. Draw the structure of the…
A: In the question 2a, the compound has D-mannose sugar linked to a phenyl ring with O-glycosidic bond…
Q: Which two enzymes produce reducing equivalents without a loss of carbon in the TCA cycle? O…
A: Question 19: Two enzyme that produce reducing equivalent without the loss of carbon in TCA cycle…
Q: 2. The kinetic effect of purely competitive inhibitor of an enzyme: (A) Increases K without…
A: Hi. Thank you for the question. As per the honor code, we are allowed to answer three sub-parts at a…
Q: 3. When the cellular energy charge is high the cells diverts into fatty acid synthesis. A. pyruvate.…
A: Glucose is the primary source of energy for the body. Glucose is metabolized through the glycolytic…
Q: reaction as a function of substrate concentration. Ex- plain why the maximal velocity can be…
A: Enzyme kinetics is the study of the rate of enzyme catalyzed bio chemical reactions and also we can…
Q: Which of the following is the primary method by which cyclin proteins are regulated to influence…
A: A. Transcriptional upregulation and translation followed by targeted ubiquitin-mediated degradation…
Q: (d) ( through the disulfide bridge. If this bridge were found for the two joined amino acids free in…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: 5' 3' For numbers 6 to 10, refer to the image above and answer the questions. 9. How are Okazaki…
A: Okazaki fragments : These are pieces of DNA which are the transient components of the lagging strand…
Q: Give 5 examples of molybdenum complexes. State their physical and chemical properties and their…
A: The atomic number of molybdenum is 42 and it is represented by the symbol 'Mo'. On the earth,…
Q: Lys and Arg Glu and Lys Pro and Asp Among these amino acid combinations listed above, only the…
A: Proteins are composed of a linear chain of amino acids attached together via peptide bonds. All…
Q: Begining with 1 M concentrations of each reactant and product at pH=7 and 25.0 degrees C, calculate…
A: There is an error in the lactic acid fermentation reaction given in question. The correct…
Q: Which of the following statements is TRUE for nonpolar amino acid residues of polypeptides or…
A: They are hydrophilic and found buried within proteins FALSE. Water soluble proteins contain…
Q: he figure shows that the average distance between base pairs measured parallel to the axis of a DNA…
A: The nucleic acid polymer has nucleotide as its monomeric unit. synthesis of nucleotides is an…
Q: Please discuss any two of the structures and functions of these 4 molecules. What do they have in…
A: 1. Main carbohydrate storage in plants. 2. Monomer - Alpha glucose 3. 1,4 -glycosidic bond in…
Q: 5' 3' For numbers 6 to 10, refer to the image above and answer the questions. 6. Which among the two…
A: Hi! Thanks for your question. As you have posted multiple questions and have not mentioned which one…
Q: II. Effect of temperature Observation(Time taken for the disappearance of blue-black colour) Test…
A: Introduction: Enzymes are organic biocatalysts that fasten the rate of chemical reaction that is…
Q: 7. A 22-year-old patient suffering argininosuccinic aciduria from little was prescribed the…
A: Arginosuccinic aciduria is a genetic disorder of the urea cycle. a) Scheme of ammonia…
Q: what is the chemistry of nucleosides?
A: Nucleosides are nothing but glycosamines whose analogues are used as anti cancer agents or antiviral…
Q: Given a Glucuromic acid omd glutathione for A) are impartantto PhaseI xemabistic melabolism B)…
A: Glucuronic acid is a sugar carboxylic acid which is generated by the oxidation of the C-6 carbon of…
Q: When the blood glucose is low, insulin is released from the pancreas to maintain glucose…
A: Insulin is a polypeptide hormone produced by the beta-cells of the islets of Langerhans (of…
Q: Using the concept of complementary base pairing, write the complementary DNA strands, with their 5'…
A: The DNA molecule generally has two strands that wind around one another to form a shape is generally…
Q: The enzyme BURT was found to function at V0=250 uM/min with a Km=15.0 uM when [S]=10.0 uM. What is…
A: Enzymes are protein molecules that increase the rate of reactions by decreasing the activation…
Q: estion properly and accordingl
A: Saponification is the process of forming a metallic salt of a fatty acid, which is referred to as a…
Q: Examine the cyclic structure of sugarls below. Which in the statements best describe the structures?…
A: The structure of monosaccharides can be represented by the Fischer projection and Haworth…
Q: Study the given structures below. Which of the following are enantiomers? * H- OH но- - H OH но- -H…
A: Carbohydrates or carbs are maconutrient consisting of Carbon, hydrogen and oxygen atoms. In nature…
Q: AP is a 35-yr old male presents with hypertension. His medications were known to work by inhibiting…
A: Any of several naturally occurring amines that act as neurotransmitters and hormones in the body is…
Q: Describe the basic features of the DNA double helix
A: DNA is Deoxyribo Nucleic acid . This is the biomolecule that is responsible for heredity in almost…
Q: Kappa- and Iota- carrageenans contain 3,6-anhydro-a-D-galactopyranosyl residues. True False
A: Carrageenans are a family of hydrocolloidsh used for thickening, stabilising, and gelling solutions…
Q: Both reducing monosaccharide and disaccharide give positive result in Barfoed's test. Which of the…
A: Barfoed's test is done to differentiate between monosaccharide and disaccharide.
Q: In the iodine clock experiment, if you increase the volume of vitamin C used, would the reaction…
A: The iodine clock experiment or reaction is the very famous experiment for the understanding of…
Step by step
Solved in 2 steps
- These are performance curves for two oxygen binding proteins. While we didn't go over the curves themselves in lecture, what are the axis labels? Myoglobin 0.8 0.6 V 0.4 0.2 I 0.0 25 50 1.0 Hemoglobin P50 = 26 torr 75 I 100 The y-axis is the fractional saturation of the protein by oxygen The x-axis is related to the concentration of oxygen to which the protein is exposed. The y-axis is the concentration of oxygen in the air. The x-axis is the fractional saturation of the protein by oxygenTrue or false? The plasma proteins suspended in blood cross the capillary cell membrane and enter the tissue fluid via facilitated diffusion. Explain your thinking.O2-binding curves 1 0.9 0.8 2 0.7 3 0.6 0.5 0.4 0.3 0.2 0.1 100 120 20 40 60 80 po2 (torr) Fractional Saturation
- Select the hemoglobin variant(s) that are described by each statement. (a) The variant least likely to cause pathological symptoms. (b) The variant(s) likely to show pl values different from that of HbA on an isoelectric focusing gel. (c) The variant most likely to show a decrease in BPG binding and an increase in the overall affinity of the hemoglobin for oxygen. Answer Bank Hb Milwaukee Hb Cowtown Hb Memphis Hb Philly Hb Providence Hb Bibba HbSFigure 5 shows oxyhemoglobin dissociatlon curves at pH 7.2 and pH 7.4. Which of the following is true at PO2 less than 40 mm Hg? 27. % saturation af haemogiobin 100 pH 7.4 80 60 pH 7.2 40 + 20 10 20 30 40 50 60 70 Po; (mm Hg) Figure 5 A. Hemoglobin retains less O2 at pH 7.4 compared to pH 7.2. B. Hemoglobin retains less O2 at pH 7.2 compared to pH 7.4. C. The release of O2 from hemoglobin is not influenced by the production of CO2. D. At pH 7.2 where CO2 production is less than pH 7.4, hemoglobin releases less O2.Q) Following an intensive course of chemotherapy, a 48-year-old woman had a thorough laboratory evaluation, selected results of which are: Hemoglobin 8 g/dL, hematocrit 32% Arterial blood gases: pH 7.38, Pa.CO₂ 42 mm Hg, bicarbonate 25 mEq/L, Pa.O2 62 mm Hg, O₂ saturation 92%. Given that the O2 binding capacity of hemoglobin is 1.34 ml/g, calculate the O2 capacity of her hemoglobin. A) 9.86 ml/dL B) 9.86 mm Hg C) 9.86 mEq/L D) 10.72 ml/dL E) 10.72 mEq/L Ans: D 6.11. Following an intensive course of chemotherapy, a 48-year-old woman had a thorough laboratory evaluation, selected results of which are: Hemoglobin 8 g/dL, hematocrit 32% Arterial blood gases: pH 7.38, Pa.CO₂ 42 mm Hg, bicarbonate 25 mEq/L, Pa.O₂ 64 mm Hg, O₂ saturation 92%. Given that the O2 binding capacity of hemoglobin is 1.34 ml/g, calculate the O2 content of her arterial hemoglobin. A) 9.86 ml/dL B) 9.86 mm Hg C) 9.86 mEq/L D) 10.72 ml/dL E) 10.72 mEq/L Ans: A
- Hand written plz Q5/ Using lumped parameters model method find the following: 1- Sketch a network for the system shown in the figure? 2- Drive the losses equations. 3- What is the source of the resistance in the lungs? Figure (2) CO₂, other gases Air Lungs Circulatory system Body Kidneys Heart + Ingestion (food, drink) kut Excretion ndigested food) Excretion (urine)Below is the O2 binding curve for adult Hb in whole blood (containing BPG) shown in red (labelled Hb). A Hb 20 40 60 80 100 pO2 (torr) a. Which curve is the best representation for stripped Hb (pure hemoglobin with heme, but no other small allosteric molecules associated)? [ Select ] b. Which curve has the lowest affinity (as measured by the p5o)? [ Select ] c. Which curve lacks cooperativity? [ Select ] Fraction of Hb bound with Oxygen 0.2 0.4 0.6 0.8 0'0 >Hand written plz Q5/ Using lumped parameters model method find the following: 1- Sketch a network for the system shown in the figure? 2- Drive the losses equations. 3- What is the source of the resistance in the lungs? Ingestion (food, drink) Figure (2) CO₂ other gases Lungs Circulatory systems Kidney's S Heart Excretion (urine) Excretion ndigested food) Body