CH3 CH3 + H3N-C-C H2N-C-C OH H H Zwitterionic Uncharged

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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At a pH equal to the isoelectric point of alanine, the net charge on alanine is zero. Two structures can be drawn that have a net charge of zero, but the predominant form of alanine at its pI is zwitterionic.
(a) Why is alanine predominantly zwitterionic rather than completely uncharged at its pI?
(b) What fraction of alanine is in the completely uncharged form at its pI? Justify your assumptions.

CH3
CH3
+
H3N-C-C
H2N-C-C
OH
H
H
Zwitterionic
Uncharged
Transcribed Image Text:CH3 CH3 + H3N-C-C H2N-C-C OH H H Zwitterionic Uncharged
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