CASE STUDY # 2A 2-year-old black girl is being seen by the hematologist after her pediatrician found her to beseverely anemic with splenomegaly and jaundice. Her mother gives a possible history of a “bloodproblem" in her family but doesn't know for sure. Her hemoglobin electrophoresis was normal, andthe complete blood count (CBC) revealed a normocytic anemia. The platelet and white blood cellcounts are normal. On the peripheral smear, there are many bizarre erythrocytes, includingspiculated cells. A diagnosis of pyruvate kinase deficiency is made.6. In the RBCS of the patient described above, which of the following would be expected? A. ADP to ATP ratios would be elevated above normal.B. NADP+ would increase relative to NADPH.C. Ribulose 5-phosphate levels would decrease.D. NADH to NAD+ ratios would decrease.E. Methemoglobin levels would increase.Explanation for answer in no. 6:

The red blood cells (RBCs) are the most important blood cells. They are in charge of transporting…

Answered: CASE STUDY # 2 A 2-year-old black girl…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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