CASE STUDY # 2A 2-year-old black girl is being seen by the hematologist after her pediatrician found her to beseverely anemic with splenomegaly and jaundice. Her mother gives a possible history of a “bloodproblem" in her family but doesn't know for sure. Her hemoglobin electrophoresis was normal, andthe complete blood count (CBC) revealed a normocytic anemia. The platelet and white blood cellcounts are normal. On the peripheral smear, there are many bizarre erythrocytes, includingspiculated cells. A diagnosis of pyruvate kinase deficiency is made.6. In the RBCS of the patient described above, which of the following would be expected? A. ADP to ATP ratios would be elevated above normal.B. NADP+ would increase relative to NADPH.C. Ribulose 5-phosphate levels would decrease.D. NADH to NAD+ ratios would decrease.E. Methemoglobin levels would increase.Explanation for answer in no. 6:

The red blood cells (RBCs) are the most important blood cells. They are in charge of transporting…

Answered: CASE STUDY # 2 A 2-year-old black girl…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Based on the below blood typing result, identify the blood type
Case Study #8: A 35-year -old Native-American male presents in the clinic with a complaint of recurrent low-grade fevers, sweating, weakness, muscle pains and a loss of about 10% of his body weight over a 4 month period. The worsening weakness and muscle pain prompted the visit. The patient reports that he has been working on a bison slaughter line owned by his tribe, and blood and tissue juices often splash in his face or contaminate minor hand and arm injuries. He likes to hunt and fish. He is married and has two children. He eats fairly well, but he has not been as hungry lately. He had rheumatic fever as a child and was in a fairly serious car accident three years earlier, resulting in a leg broken in three places. He feels he was physically fit prior to the past 4 months. He likes to play basketball and softball. He has had all the usual childhood immunizations, but does not see the doctor often. On physical examination, the patient has a temperature of 101F. He has mildly swollen…
Compute for the absolute count of patients A and B PATIENT A WBC count = 6 x 109/L Differential count Absolute count Neutrophils = 65% Lymphocytes = 20% Monocytes = 13% Eosinophils = 2% PATIENT B WBC count = 18 x 109/L Differential count Absolute count Neutrophils = 65% Lymphocytes = 20% Monocytes = 10% Eosinophils = 5% Give an impression of their results. (Indicate whether the cells are increased or decreased using the proper terminologies. Indicate also whether the increased or decreased values are absolute or relative)
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