A 25-year-old man comes to the emergency department because of a 2-day history of fever and rash. He has a history of complex partial sezure secondary to an arteriovenous malformation. He has had breath through seizure several times each despite treatment with several medication regions. Initially, treatment with phenytoin, which caused sedation. Two weeks ago, he was stitched to valproic acid and lamotrigine. He states that he has not had any seizure during topiramate and phenytoin, which caused sedation. Two weeks ago, he was switched valproic acid and lamotrigine. He states that he was not ad nay seizure during this time, and he finished his sample package of lamotrigine. He is awake and alert but appears ill. Vital signs are temperature 39.0 oC (102.2 oF), pulse 1110/min, respiration 22/min. and blood pressure 130/90 mm Hg. Examination shows extensive bullae, especially over the hands and feet. There are erosive lesions over the mouth and genital area. Which of the following drugs is the most likely cause of this patient’s dermatologic symptoms? Carbamazepine Lamotrigine Phenytoin Topiramate Valproic acid

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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A 25-year-old man comes to the emergency department because of a 2-day history of fever and rash. He has a history of complex partial sezure secondary to an arteriovenous malformation. He has had breath through seizure several times each despite treatment with several medication regions. Initially, treatment with phenytoin, which caused sedation. Two weeks ago, he was stitched to valproic acid and lamotrigine. He states that he has not had any seizure during topiramate and phenytoin, which caused sedation. Two weeks ago, he was switched valproic acid and lamotrigine. He states that he was not ad nay seizure during this time, and he finished his sample package of lamotrigine. He is awake and alert but appears ill. Vital signs are temperature 39.0 oC (102.2 oF), pulse 1110/min, respiration 22/min. and blood pressure 130/90 mm Hg. Examination shows extensive bullae, especially over the hands and feet. There are erosive lesions over the mouth and genital area. Which of the following drugs is the most likely cause of this patient’s dermatologic symptoms?

  1. Carbamazepine
  2. Lamotrigine
  3. Phenytoin
  4. Topiramate
  5. Valproic acid
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