Calculate the amount of ingredients and create a batch sheet.   What will be the correct storage and expiry date of this product?   What could be the therapeutic indication for this product?   What is the purpose of the glycerol?   Could this be made on the bench where you reconstitute mixtures and mix creams?   If yes/no, why/why not?

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Case Study 5

 

Sodium Bicarbonate Ear Drops

 

Next door to your pharmacy is an ENT clinic and the Doctors have a standing order for “NaHCO3 ear drop” for clinic use. You have a master formula and need to make one batch to replenish their inventory. You are going to make five 10 mL bottles.

 

Formulation

 

Sodium bicarbonate 5

Glycerol 30

Purified water to 100

Dissolve without the aid of heat.

 

Questions

 

Calculate the amount of ingredients and create a batch sheet.

 

What will be the correct storage and expiry date of this product?

 

What could be the therapeutic indication for this product?

 

What is the purpose of the glycerol?

 

Could this be made on the bench where you reconstitute mixtures and mix creams?

 

If yes/no, why/why not?

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