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(a) Using "excretion rate" method and "amount to be excreted" method, estimate k, ku, and fe of the drug.

(a) Using "excretion rate" method and "amount to be excreted" method, estimate k, ku, and fe of the drug.

Phlebotomy Essentials
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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2. Time (h) O246 0 6 8 12 24 A patient was given a 50 mg IV bolus dose of a drug and periodic urine samples were collected. The observations are as follows: Urine volume Collected (ml) 120 180 89 340 178 950 Urine Time Mid-Point Conc interval of Time Interval (h) (µg/ml) (h) 133 50 63 10 18 2 Amt Excreted in Time Inteval (mg) Excretion Cumulative Rate (mg/h) Amount Excreted (mg) (a) Using "excretion rate" method and "amount to be excreted" method, estimate k, ku, and fe of the drug. Amount Remaining to be Excreted (mg)
Transcribed Image Text:2. Time (h) O246 0 6 8 12 24 A patient was given a 50 mg IV bolus dose of a drug and periodic urine samples were collected. The observations are as follows: Urine volume Collected (ml) 120 180 89 340 178 950 Urine Time Mid-Point Conc interval of Time Interval (h) (µg/ml) (h) 133 50 63 10 18 2 Amt Excreted in Time Inteval (mg) Excretion Cumulative Rate (mg/h) Amount Excreted (mg) (a) Using "excretion rate" method and "amount to be excreted" method, estimate k, ku, and fe of the drug. Amount Remaining to be Excreted (mg)
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