(c) The following QSAR equation is related to the mutagenic activity of a series of nitrosoamines; log 1/ C = 0.92 πT +2.08σ - 3.26 (n = 12, r² = 0.794, s = 0.314). What sort of substituent is likely to result in high mutagenic activity? Suggest 2 substituents that meet this criterion. (5 marks)
(c) The following QSAR equation is related to the mutagenic activity of a series of nitrosoamines; log 1/ C = 0.92 πT +2.08σ - 3.26 (n = 12, r² = 0.794, s = 0.314). What sort of substituent is likely to result in high mutagenic activity? Suggest 2 substituents that meet this criterion. (5 marks)
Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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The following QSAR equation is related to the mutagenic activity of a
series of nitrosoamines;
log 1/ C = 0.92 πT +2.08σ - 3.26 (n = 12, r² = 0.794, s = 0.314).
What sort of substituent is likely to result in high mutagenic activity?
Suggest 2 substituents that meet this criterion.
(5 marks)
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