(၁) Azidothymidine (AZT), shown in Figure Q10(c), is a prodrug and acts as a chain terminator. HO CH3 Azidothymidine Figure Q10(c) (i) What is the therapeutic use of AZT? (1 marks) (ii) Define the meaning of a prodrug. (1 marks) (iii) Describe the mechanism of action of AZT. (5 marks)
(၁) Azidothymidine (AZT), shown in Figure Q10(c), is a prodrug and acts as a chain terminator. HO CH3 Azidothymidine Figure Q10(c) (i) What is the therapeutic use of AZT? (1 marks) (ii) Define the meaning of a prodrug. (1 marks) (iii) Describe the mechanism of action of AZT. (5 marks)
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter23: Amines
Section23.6: Reactions With Acids
Problem 23.9P
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![(၁)
Azidothymidine (AZT), shown in Figure Q10(c), is a prodrug and acts as
a chain terminator.
HO
CH3
Azidothymidine
Figure Q10(c)
(i) What is the therapeutic use of AZT?
(1 marks)
(ii) Define the meaning of a prodrug.
(1 marks)
(iii) Describe the mechanism of action of AZT.
(5 marks)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fe8d3d618-55be-44c2-9091-0170276b597d%2F3030c66e-740b-43f6-9028-24f9922ff34a%2Fguxmryj_processed.jpeg&w=3840&q=75)
Transcribed Image Text:(၁)
Azidothymidine (AZT), shown in Figure Q10(c), is a prodrug and acts as
a chain terminator.
HO
CH3
Azidothymidine
Figure Q10(c)
(i) What is the therapeutic use of AZT?
(1 marks)
(ii) Define the meaning of a prodrug.
(1 marks)
(iii) Describe the mechanism of action of AZT.
(5 marks)
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