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- Question 6 a) Explain the general advantages in the use of radiopharmaceuticals for treatment as opposed to irradiation using external sources of radiation. b) Relate these advantages to explain why radiopharmaceuticals are often used in the treatment of i) prostate cancer (brachytherapy)ii) thyroid cancer (iodine-131 treatment)Question 5 a) Explain the general diagnostic principles using radiopharmaceuticals by which medical images may obtained. b) Describe the use of technetium-99m-MDP. c) Describe the use of 1251 radioisotope. [Suggested word count 270] [2.2]Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives. The given question to me is: What is a pharmacopeial monograph? Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives.
- We are no longer going to use propofol, describe the procedure to discard it.QUESTION 1 A. Define equilibrium constant of a drug B. Discuss the relationship between the equilibrium constant, affinity, potency and the response of a drug C. Discuss four factors that may affect a drug responseQuestion 4 a) Explain the importance of reducing exposure dose and time to a patient undergoing a diagnostic X-ray examination. Describe ways to achieve this. b) Calculate the wavelength of the most energetic X-rays produced by tube operating at pd of [1.4]
- From the given situations, explain whether its solution requires a qualitative analysis, quantitative analysis, characterization analysis, and/or fundamental analysis. More than one type of analysis can be applied for some problems. 1. The structure of a mutated coronavirus strain found in the Philippines needs to be determined. 2. The residents of a prominent subdivision in Iloilo near a waste disposal site are concerned that it is leaking contaminants into their groundwater. 3. The Iloilo Museum of Contemporary Art (ILOMOCA) is concerned that the recently acquired oil painting is not authentic. 4. The Iloilo International Airport needs more reliable scanner for detecting explosive materials in luggage. 5. An oil spill in Barrio Obrero last July 2020 leaked around 250,000 L of fuel reached the neighboring towns and the island of Guimaras.Question 1: Suppose you have given 5 tablets weighing 449mg, 450mg, 448mg, 451mg and 453mg, respectively. Calculate 300 mg equivalent sample weight for assay. The product claim is 500 mg Vitamin C is present in each tablet. Question 2: Volume of the standard sodium edetate is 12.6 mL (calculated after the assay of Zinc Sulfate Syrup). Determine the % of potency of the drug considering the claimed dose is 11.5Name the three basic classes of drug targets in medicinal chemistry and indicate, which are the most/least important as targets for biologics? I don't sure if I answer these questions correctly. Hope someone can give me confirmation and explain to me how enzymes will be affected by bioloigcs? My answer so far: The three common classes of drug targets are; receptors, nucleic acid, and enzymes. As a target for biologics, the least important will be a nucleic acid, and the most important will be receptor and second enzymes. Biologic drugs such as monoclonal antibodies will bind to the antigens, which are overexpressed receptor that need to be deactivated. In this case, the monoclonal antibodies will act as an antagonist and block the ligand from binding to the antigens, which are extensively presented in cancer cells. In addition, it can also affect enzymes by.......?
- Enumerate and describe at least three (3) big scale pharmaceutical methods on reducing particle size.apa format no plagiarism Describe the FDA approval process for assessing the safety and efficacy of a newly developed drug. What are advantages and disadvantages of this process?In order to market any drug in the United States, a pharmaceutical company must submit Investigational New Drug (IND) and New Drug Application (NDA) to the FDA. What are the differences between these two applications? What information about the drug is expected to contain in these application files?