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3. As discussed in class, single lipid layers are a great way to package materials (like drugs or vaccines) so that they can cross the lipid membrane and get into a cell. i) Discuss why most molecules can not cross the lipid bilayer. ii) Discuss why drugs, when packaged in a lipid membrane, can pass through the lipid bilayer. iii) Hypothesize how you would get materials into the lipid membranes shown below and why the thermodynamics of the system force the lipid membrane into spheres. iv. Would it be beneficial to add cholesterol to these layers to facilitate the transport of materials? Lipoplex $10 Lipid-polymer hybrid nanoparticle (Lipid bilayer) Lipid nanoparticle Lipid-polymer hybrid nanoparticle (Lipid monolayer))

3. As discussed in class, single lipid layers are a great way to package materials (like drugs or vaccines) so that they can cross the lipid membrane and get into a cell. i) Discuss why most molecules can not cross the lipid bilayer. ii) Discuss why drugs, when packaged in a lipid membrane, can pass through the lipid bilayer. iii) Hypothesize how you would get materials into the lipid membranes shown below and why the thermodynamics of the system force the lipid membrane into spheres. iv. Would it be beneficial to add cholesterol to these layers to facilitate the transport of materials? Lipoplex $10 Lipid-polymer hybrid nanoparticle (Lipid bilayer) Lipid nanoparticle Lipid-polymer hybrid nanoparticle (Lipid monolayer))

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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3. As discussed in class, single lipid layers are a great way to package materials (like drugs or vaccines) so that they can cross the lipid membrane and get into a cell. i) Discuss why most molecules can not cross the lipid bilayer. ii) Discuss why drugs, when packaged in a lipid membrane, can pass through the lipid bilayer. iii) Hypothesize how you would get materials into the lipid membranes shown below and why the thermodynamics of the system force the lipid membrane into spheres. iv. Would it be beneficial to add cholesterol to these layers to facilitate the transport of materials? Lipoplex $10 Lipid-polymer hybrid nanoparticle (Lipid bilayer) Lipid nanoparticle Lipid-polymer hybrid nanoparticle (Lipid monolayer))
Transcribed Image Text:3. As discussed in class, single lipid layers are a great way to package materials (like drugs or vaccines) so that they can cross the lipid membrane and get into a cell. i) Discuss why most molecules can not cross the lipid bilayer. ii) Discuss why drugs, when packaged in a lipid membrane, can pass through the lipid bilayer. iii) Hypothesize how you would get materials into the lipid membranes shown below and why the thermodynamics of the system force the lipid membrane into spheres. iv. Would it be beneficial to add cholesterol to these layers to facilitate the transport of materials? Lipoplex $10 Lipid-polymer hybrid nanoparticle (Lipid bilayer) Lipid nanoparticle Lipid-polymer hybrid nanoparticle (Lipid monolayer))
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