Exercise B: Peptide Bond Formation Figure 2 shows two individual amino acids, and then those same two amino acids after they have been linked together by a peptide bond to form a dipeptide. Addition of more amino acids linked by peptide bonds would form a polypeptide, the precursor to a functional protein. нн +| | || H-N-C-Ĉ-0 H. +! | || H-N-C-ċ –0 H. H H H +| | || H-N-C-C-N-C-C- + H CH2 CH2 H CH2 H. CH2 SH SH NH, NH, Figure 2. Formation of a peptide bond between two amino acids. Answer the below questions in your own document. 1. Which two amino acids are shown on the left side of Figure 2? Use the Figure 3.2 from your text to answer this. 2. To which chemical groups do these amino acids belong? 3. Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules! On the dipeptide shown in Figure 2, label the peptide bond that was formed when the two individual amino acids were joined. Label the free amino and carboxyl groups at the ends of this dipeptide (not in the R groups). These are often referred to as the N- terminus (amino-terminus) and the C-terminus (carboxyl-terminus) of a peptide or polypeptide. (Note: "peptide" refers to a chain of a small number of amino acids, whereas "polypeptide" refers to a longer chain, potentially that corresponding to an entire protein.)

Biology 2e
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ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
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Chapter3: Biological Macromolecules
Section: Chapter Questions
Problem 23CTQ: Amino acids have the generic structure seen below, where R represents different carbon-based side...
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Exercise B: Peptide Bond Formation
Figure 2 shows two individual amino acids, and then those same two amino acids after
they have been linked together by a peptide bond to form a dipeptide. Addition of
more amino acids linked by peptide bonds would form a polypeptide, the precursor to a
functional protein.
нн
+| | ||
H-N-C-Ĉ-0
H.
+! | ||
H-N-C-ċ –0
H.
H
H
H
+| | ||
H-N-C-C-N-C-C-
+
H
CH2
CH2
H
CH2
H.
CH2
SH
SH
NH,
NH,
Figure 2. Formation of a peptide bond between two amino acids.
Answer the below questions in your own document.
1. Which two amino acids are shown on the left side of Figure 2? Use the Figure
3.2 from your text to answer this.
2. To which chemical groups do these amino acids belong?
3. Were you able to identify their chemical characteristics based on your rules? If
not, you should go back and revise your rules!
On the dipeptide shown in Figure 2, label the peptide bond that was formed when the
two individual amino acids were joined. Label the free amino and carboxyl groups at
the ends of this dipeptide (not in the R groups). These are often referred to as the N-
terminus (amino-terminus) and the C-terminus (carboxyl-terminus) of a peptide or
polypeptide. (Note: "peptide" refers to a chain of a small number of amino acids,
whereas "polypeptide" refers to a longer chain, potentially that corresponding to an
entire protein.)
Transcribed Image Text:Exercise B: Peptide Bond Formation Figure 2 shows two individual amino acids, and then those same two amino acids after they have been linked together by a peptide bond to form a dipeptide. Addition of more amino acids linked by peptide bonds would form a polypeptide, the precursor to a functional protein. нн +| | || H-N-C-Ĉ-0 H. +! | || H-N-C-ċ –0 H. H H H +| | || H-N-C-C-N-C-C- + H CH2 CH2 H CH2 H. CH2 SH SH NH, NH, Figure 2. Formation of a peptide bond between two amino acids. Answer the below questions in your own document. 1. Which two amino acids are shown on the left side of Figure 2? Use the Figure 3.2 from your text to answer this. 2. To which chemical groups do these amino acids belong? 3. Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules! On the dipeptide shown in Figure 2, label the peptide bond that was formed when the two individual amino acids were joined. Label the free amino and carboxyl groups at the ends of this dipeptide (not in the R groups). These are often referred to as the N- terminus (amino-terminus) and the C-terminus (carboxyl-terminus) of a peptide or polypeptide. (Note: "peptide" refers to a chain of a small number of amino acids, whereas "polypeptide" refers to a longer chain, potentially that corresponding to an entire protein.)
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