Because offspring inherit the mitochondrial genome only from the mother, evolutionarily the mitochondrial genome in males encounters a dead end. The mitochondrial genome in males has no significant impact on the genetic information of future generations. Scientists have proposed that this can result in an accumulation of mutations that have a negative impact on genetic fitness of males but not females. Experiments with Drosophila support this possibility. What experimental data or evidence would you want to evaluate or consider to determine if an accumulation of mtDNA mutations negatively impacts the fitness of males of any species?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Because offspring inherit the mitochondrial genome only from the
mother, evolutionarily the mitochondrial genome in males encounters
a dead end. The mitochondrial genome in males has no significant
impact on the genetic information of future generations.
Scientists have proposed that this can result in an accumulation of
mutations that have a negative impact on genetic fitness of males
but not females. Experiments with Drosophila support this possibility.
What experimental data or evidence would you want to evaluate
or consider to determine if an accumulation of mtDNA mutations
negatively impacts the fitness of males of any species?

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