Aspirin is a weak acid (figure below) that is taken up into the bloodstream by diffusion through cells lining the stomach and the small intestine. One of the two forms ofaspirin shown below can cross the plasma membrane of a cell. The pH of the stomach is about 1.5 and that of the lumen of the small intestine is about 6.0.pK= 3.5Huncharged formcharged formTheform can cross the lipid bilayer more effectively and thus, majority of the aspirin will be absorbed into the bloodstream through theuncharged; small intestineO charged; small intestineO uncharged; stomach liningcharged; stomach lining

Aspirin is an analgesic with structure below: It is a weak acid which can dissociate to form…

Answered: Aspirin is a weak acid (figure below)…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

If the protein you are studying is known to bind the molecule shown below, what types of amino acids would you expect to be forming interactions at each of the numbered positions. Explain your reasoning for your choices 2 0 N* H- H H. 4. 3. 1,
The transport of aspirin (pKa = 3.5, structure shown here) from the digestive tract to the circulation occurs by nonmediated absorption into cells lining the stomach (where pH = 0.8) and the small intestine (where pH 6.0). Do you expect absorption to be faster in the stomach or in the small intestine?
Long chains of beta glucose monomers are held together in microfibril bundles by bonds Vanderwaals Interaction ionic covalent hydrogen In a fat molecule a glycerol is covalently bonded to fatty acid tails by a glycosidic link a hydrogen bond an ionic bond an ester link If the R group of an amino acid is nonpolar, it probably consists of one or more methyl groups hydroxyl groups amino groups hydrophilic groups
You have a mixture of positive, negative and neutral proteins. In order to obtain a pure positively charged protein, you can pass this mixture through a column containing G-50 coarse beads Anion Exchanger beads Cation Exchanger beads G-50 superfine beads
Select ALL statements that are true about the isoelectric point (pI) of a protein a.Protein carries a net negative charge at its pIb.There is no net charge on the protein at its pIc.Above its pI, a protein is negatively chargedd.pI depends on the amino and carboxylic acid content of a protein
The figure below illustrates the molecular structures of two fatty acids. A B H₂C The structural formula of erucic acid and behenic acid с H₂C D erucic acid behenic acid Which of the following best explains why erucic acid is liquid at room temperature but behenic acid is solid at room temperature? O OH The presence of a double carbon to carbon bond in erucic acid prevents the molecule from packing closely together. The lack of any double carbon-carbon bonds in behenic acid causes the molecule to be come polar and therefore packed more tightly. The larger number of carbon atoms in erucic acid prevents the molecule from packing tightly together. OH The smaller number of carbon atoms in behenic acid creates stronger covalent bonds between the carbon atoms allowing for them to pack more tightly together.
Which of the following statements is TRUE for nonpolar amino acid residues of polypeptides or proteins in an aqueous solution? None of the above They are hydrophilic and found buried within proteins They are hydrophilic and found on protein surfaces They are hydrophobic and found on protein surfaces They are hydrophobic and found buried within proteins
When pharmacology researchers design drugs that must enter into cells in order to be effective, they often add functional groups to the drug to make it more likely to pass through the plasma membrane. The addition of which of the following functional groups would be most likely to increase the permeability of a drug across a membrane? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a Amino. Carboxyl. Hydroxyl. d Methyl. e Phosphate.
1- (True or False) Adjacent nucleotides are joined by covalent bonds that form between the –OH group on the 3` carbon of one nucleotide and the phosphate on the 5` carbon on the next. 2- (True or False) if a solute is in an aqueous solution, then by definition an hydration shell has formed around it. 3- (True or False) When exposed to water, phospholipids will self-organize into lipid bilayers, and spheres.
If radioactive 32P were added to the growth medium of cells, which of these would incorporate the ³2p phospholipids nucleic acids O fatty acids both phospholipids and nucleic acids amino acids
New anti-cancer agents are being developed that target fatty acid synthase (FASN) due to a requirement for lipid synthesis to promote tumor cell replication. Describe why an enzyme inhibitor targeted to the following sites would or would not work to inhibit lipid synthesis. Explain your answer. If you’re not sure whether it will work, make an argument for and against it working. ACP site on FASN The dimer interface between monomers of FASN Targeting FASN to mitochondrial matrix
A spheroidal bacterium with a diameter of 1.0 μm (micrometer, 1 μm = 10-6) contains 25,000 molecules of the protein hexokinase. What is the molar concentration of the protein inside the cell?

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