As horses get older, poor hoof and tendon health leads to joint pain, reducing a horse’s activity level.  Such a reduction can lead to other health concerns such as obesity and a decrease in energy due to lack of exercise.  A study is to be conducted to determine which of two diet supplements, Vitamin C and D-cycloserine, is more effective in promoting hoof and tendon health and reducing the onset of osteoporosis in horses.  Researchers will randomly select a total of 300 horses from ten different large animal veterinary practices around the country.  All of the horses are more than 5 years old, and their owners have given consent to participate in the study.  Changes in hoof and tendon health will be evaluated after 6 months of treatment.   What would be an advantage to adding a control group in the design of this study? Assuming a control group is added to the other two groups in the study, explain how you would assign the 300 horses to these three groups for a completely randomized design. Rather than using a completely randomized design, one group of researchers proposes blocking on clinics, and another group of researchers proposes blocking on breed of horse.  How would you decide which ONE of these two variables to use as a blocking variable?

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As horses get older, poor hoof and tendon health leads to joint pain, reducing a horse’s activity level.  Such a reduction can lead to other health concerns such as obesity and a decrease in energy due to lack of exercise.  A study is to be conducted to determine which of two diet supplements, Vitamin C and D-cycloserine, is more effective in promoting hoof and tendon health and reducing the onset of osteoporosis in horses.  Researchers will randomly select a total of 300 horses from ten different large animal veterinary practices around the country.  All of the horses are more than 5 years old, and their owners have given consent to participate in the study.  Changes in hoof and tendon health will be evaluated after 6 months of treatment.

 

  1. What would be an advantage to adding a control group in the design of this study?
  2. Assuming a control group is added to the other two groups in the study, explain how you would assign the 300 horses to these three groups for a completely randomized design.
  3. Rather than using a completely randomized design, one group of researchers proposes blocking on clinics, and another group of researchers proposes blocking on breed of horse.  How would you decide which ONE of these two variables to use as a blocking variable?
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