Arsinate binds to reduced thio groups such as those found in cystiene residues in proteins, lipoate or glutathione. The resulting inhibition leads to central nervous system pathologies. The binding of arsinate to the dihydrolipoyl groups inhibits which of the following enzyme(s)? a.succinate dehydrogenase b.malate dehydrogenase c.pyruvate dehydrogenase complex d.branched-chain amino acid dehydrogenase complex e.isocitrate dehydrogenase f.alpha-ketoglutarate dehydrogenase complex A common and effective treatment for arsenite poisoning involves administration of _____. a.aresenite chelator b.vitamin B1 c.a competitive sulfhydryl reagent d.NADPH e.a dihydrolipoyl inhibitor
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Arsinate binds to reduced thio groups such as those found in cystiene residues in proteins, lipoate or glutathione. The resulting inhibition leads to central nervous system pathologies. The binding of arsinate to the dihydrolipoyl groups inhibits which of the following enzyme(s)?
a.succinate dehydrogenase
b.malate dehydrogenase
c.pyruvate dehydrogenase complex
d.branched-chain amino acid dehydrogenase complex
e.isocitrate dehydrogenase
f.alpha-ketoglutarate dehydrogenase complex
A common and effective treatment for arsenite poisoning involves administration of _____.
a.aresenite chelator
b.vitamin B1
c.a competitive sulfhydryl reagent
d.NADPH
e.a dihydrolipoyl inhibitor
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