are necessary for cyclin-dependent kinases to work. QUESTION 13 block cyclin-dependent kinases, turning them off.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 10
The human form of Cdk1 phosphorylates a protein called Abl, which is a kinase itself. Abl is involved in advancing the cell cycle, but it is unclear how.
What problem may result if Abl is constitutively active (cannot be turned off)?
QUESTION 11
What protein complex has to get loaded onto DNA during G1 but only gets activated during S phase?
МСМ helicase
the kinetochore
The ATM DNA damage sensor
O DNA polymerase
QUESTION 12
are necessary for cyclin-dependent kinases to work.
QUESTION 13
block cyclin-dependent kinases, turning them off.
QUESTION 14
phosphorylate substrates that actually do something to move the cell cycle forward (for example, one of these phosphorylates proteins attached to
the nuclear envelope and nuclear lamina to cause nuclear envelope disassembly at the start of mitosis).
Transcribed Image Text:QUESTION 10 The human form of Cdk1 phosphorylates a protein called Abl, which is a kinase itself. Abl is involved in advancing the cell cycle, but it is unclear how. What problem may result if Abl is constitutively active (cannot be turned off)? QUESTION 11 What protein complex has to get loaded onto DNA during G1 but only gets activated during S phase? МСМ helicase the kinetochore The ATM DNA damage sensor O DNA polymerase QUESTION 12 are necessary for cyclin-dependent kinases to work. QUESTION 13 block cyclin-dependent kinases, turning them off. QUESTION 14 phosphorylate substrates that actually do something to move the cell cycle forward (for example, one of these phosphorylates proteins attached to the nuclear envelope and nuclear lamina to cause nuclear envelope disassembly at the start of mitosis).
QUESTION 16
Which is a faster process, microtubule assembly or disassembly?
Assembly
Disassembly (catastrophe)
They would occur at the same rate
QUESTION 17
Suppose you have a microtubule growing outward from a centrosome. There is a small GTP cap at the plus end of the microtubule.
Now, a microtubule associated protein (MAP) cuts the microtubule in half. What will happen to the end of the microtubule anchored to the centrosome?
O It will rapidly disassemble from the plus end (catastrophe)
It will grow until it reaches the length of the original microtubule
It will begin treadmilling
O It will detach from the centrosome
QUESTION 18
Suppose you have a microtubule growing outward from a centrosome. There is a small GTP cap at the plus end of the microtubule.
Now, a microtubule associated protein (MAP) cuts the microtubule in half. What will happen to the end of the microtubule that is NOT anchored to the centrosome?
It will rapidly disassemble from the plus end (catastrophe)
It will grow until it reaches the length of the original microtubule
It will begin treadmilling
O It will detach from the centrosome
QUESTION 19
Suppose you treat cells with a drug that blocks actin branching. What cellular functions might be disrupted?
muscle contraction
cell migration
formation of the mitotic spindle
O regulation of heterochromatin formation
Transcribed Image Text:QUESTION 16 Which is a faster process, microtubule assembly or disassembly? Assembly Disassembly (catastrophe) They would occur at the same rate QUESTION 17 Suppose you have a microtubule growing outward from a centrosome. There is a small GTP cap at the plus end of the microtubule. Now, a microtubule associated protein (MAP) cuts the microtubule in half. What will happen to the end of the microtubule anchored to the centrosome? O It will rapidly disassemble from the plus end (catastrophe) It will grow until it reaches the length of the original microtubule It will begin treadmilling O It will detach from the centrosome QUESTION 18 Suppose you have a microtubule growing outward from a centrosome. There is a small GTP cap at the plus end of the microtubule. Now, a microtubule associated protein (MAP) cuts the microtubule in half. What will happen to the end of the microtubule that is NOT anchored to the centrosome? It will rapidly disassemble from the plus end (catastrophe) It will grow until it reaches the length of the original microtubule It will begin treadmilling O It will detach from the centrosome QUESTION 19 Suppose you treat cells with a drug that blocks actin branching. What cellular functions might be disrupted? muscle contraction cell migration formation of the mitotic spindle O regulation of heterochromatin formation
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