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An attempt was made to inhibit Enzyme X by adding compounds M and L. The results are summarized in the table below: Which of the 2 compounds is the best inhibitor of Enzyme X? Show your computation. Assume equal concentrations of compound M and compound L. Km apparent, Vmax Type of Inhibition аpparent, umol/L mM/min Compound M 5.0 x 10-4 0.30 Non-competitive Compound L 2.5 x 10-2 0.40 Competitive Km Vmax Without inhibitor 5.0 x 10-4 0.40

An attempt was made to inhibit Enzyme X by adding compounds M and L. The results are summarized in the table below: Which of the 2 compounds is the best inhibitor of Enzyme X? Show your computation. Assume equal concentrations of compound M and compound L. Km apparent, Vmax Type of Inhibition аpparent, umol/L mM/min Compound M 5.0 x 10-4 0.30 Non-competitive Compound L 2.5 x 10-2 0.40 Competitive Km Vmax Without inhibitor 5.0 x 10-4 0.40

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Compute using the Ki formula

An attempt was made to inhibit Enzyme X by adding compounds M and L. The results are summarized in the table below: Which of the 2 compounds is the best inhibitor of Enzyme X? Show your computation. Assume equal concentrations of compound M and compound L. Km apparent, Vmax Type of Inhibition apparent, umol/L mM/min Compound M 5.0 x 10-4 0.30 Non-competitive Compound L 2.5 x 10-2 0.40 Competitive Km Vmax Without inhibitor 5.0 x 10-4 0.40
Transcribed Image Text:An attempt was made to inhibit Enzyme X by adding compounds M and L. The results are summarized in the table below: Which of the 2 compounds is the best inhibitor of Enzyme X? Show your computation. Assume equal concentrations of compound M and compound L. Km apparent, Vmax Type of Inhibition apparent, umol/L mM/min Compound M 5.0 x 10-4 0.30 Non-competitive Compound L 2.5 x 10-2 0.40 Competitive Km Vmax Without inhibitor 5.0 x 10-4 0.40
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