An adolescent male patient presented with pain in the calf muscles on exercise. On biopsy, an excessive amount of glycogen was found to be present in the muscle. What is the most likely enzyme deficiency?

Q: A teenager was admitted to the hospital with extreme muscle pain, lightheadedness and fatigue after…

A: Cellular respiration is a metabolic process that is made up of three metabolic pathways: glycolysis,…

Q: What is the effect of each of the 4 types of inhibitors on the initial rate of an enzyme catalyzed…

A: Inhibitors of enzyme catalyzed reactions are broadly classified into reversible and irreversible…

Q: If isolated regulatory subunits and catalytic subunits of ATCase are mixed, the native enzyme is…

A: ATcase (Aspartate transcarbamoylase) is an allosteric enzyme. It is involved in regulation of…

Q: Alkaline phosphatase had an optimal temperature of 37°C. If you tested the enzyme at 37°C, 50°C, and…

A: An enzyme is active within a narrow range of temperature. The temperature at which an enzyme shows…

Q: What are the rate constants for the enzyme-catalyzed reaction?

A: Enzymes are a type of proteins that acts as biological catalysts to accelerate the rate of a…

Q: Lead exerts its poisonous effect on enzymes by two mechanisms. Which mechanism is irreversible and…

A: The prime targets to lead toxicity are the heme synthesis enzymes, thiol-containing antioxidants and…

Q: What will happen to the rate of FPP synthesis when FPP concentration is very high Inhibition of an…

A: FPP is farensyl pyrophosphate, one of the intermediates in cholesterol biosynthesis. It is a huge…

Q: A allosteric regulator the rate of an enzyme-catalyzed reaction by inducing the active site of the…

A: Enzymes are macromolecular biological catalysts that accelerate chemical reactions. The molecules…

Q: Phenylketonuria can result from a mutation in the( PAH) Phenyl Alanine Hydroxylase gene.

A: Phenylketonuria is a genetic defect that is caused by the deficiency of phenylalanine hydroxylase…

Q: Orotic aciduria results when one of the enzyme activities of UMP synthetase is absent. This syndrome…

A: Orotic aciduria is a hereditary disorder related to metabolism. Orotic aciduria is one of the…

Q: explain the allosteric regulation of glycogen synthase and glycogen phosphorylase?

A: Gluconeogenesis is the metabolic pathway that results in the generation of glucose from certain…

Q: In the majority of cases, amino acid catabolism can be broken down into a two-step process;…

A: The catabolism of the amino acids begins with the removal of the amino group. The amino group can be…

Q: What happens to the enzyme’s native conformation once it is denatured? What structural organization…

A: " Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Consider the following statements: (1) All of the B vitamins are water-soluble. (2) The induced-fit…

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: 3 yr-old presented with extreme fatigue, intolerance to physical activity and an enlarged liver.…

A: Lactate is a carbohydrate that is produced as final byproduct of anaerobic glycolysis.

Q: The text describes a form of gout that results from HGPRT deficiency. Propose one or two additional…

A: In the case of humans, uric acid formation occurs due to the breakdown of purines. Our kidneys are…

Q: The teenager had intense running exercise causing conversion of sugar to pyruvate to lactate. The…

A: Sugars are converted to pyruvate through the process of glycolysis that occurs in the cytoplasm.…

Q: What is the major activator (non-allosteric, direct-activator) of phosphorylase?  How does this…

A: The entire number of biochemical processes involved in sustaining the living circumstances of cells…

Q: Please draw all of the structures of the intermediates and names of all reactants, intermediates and…

A: Glycolysis is the metabolic pathway that stepwise oxidises glucose to pyruvate to produce ATP and…

Q: significance of transition state stabilisation and how this impacts the free energy of activation in…

A: Transition state stabilization is crucial in enzyme-catalyzed reactions as it lowers the energy…

Q: What is the net gain in ATP for ß-oxidation of palmitic acid (a sixteen-carbon fatty acid)?

A: For the complete oxidation of palmitic acid, it is first activated to its acyl-CoA form. This…

Q: Explain why catalase activity is lower at: i. Low temperature ii. High temperature

A: Catalase is an important enzyme present in all aerobic organisms requiring oxygen for survival. It…

Q: How temperature, pH and salt affects the enzyme activity in terms of protein structure (primary,…

A: Most enzymes in cellular systems are protein molecules. They are biocatalysts that increase the…

Q: The highest energy point of the serine protease reaction is the formation of the tetrahedral…

A: The serine protease reaction is a chemical reaction in which the enzyme breaks the peptide bond…

Q: Please answer this question and the highlighted question is wrong please explain why and give me the…

A: The correct answer is option cThe transition state of an enzyme has the highest free energy in…

Q: Amino acid degradation and biosynthesis are related metabolic processes, but they are not identical.…

A: Amino acids are organic compounds that comprise amino & carboxylate functional groups in…

Q: Anemic patient diagnosed clinically through his symptoms which are: weakness, fatigue, shortness of…

A: Pyruvate kinase deficiency (PKD) is a rare genetic disorder characterized by the premature…

Q: A) Effect of Enzymes on Reactions Which of the following effects (a-g) would increase the rate of an…

A: We know Keq is the equilibrium constant and it is equal to .Here;[P] is the concentration of product…

Q: Human xanthine oxidase catalyzes the oxidation of hypoxanthine to xanthine and can further catalyze…

A:

Q: If you can clearly visualize the chymotrypsin mechanism of action, you should be able to picture the…

A: Enzymes are substance produced by a living organism which acts as a catalyst to perform specific…