All amino acids have two ionizable functional groups: an a-amino group (average pK₁ of 9.4) and an o-carboxylic acid group (average pK₁ of 2.2). Lysine also has an ionizable side chain (R group) with a pK, of about 10.5. One of the possible ionization states of lysine is shown in the image. || H₂N-CH-C-OH I CH₂ 1 CH₂ T Incorrect CH₂ 1 CH₂ +1 NH3 At what pH would the structure be the predominant ionization state? Consider the ionization state of all three of the functional groups. 10.5 The protonated form of the R group of lysine is shown in the structure. The ratio of the charged (protonated) form to the deprotonated form depends on the pK₁ of the R group and the pH of the solution. Select all the pH values at which the charged form of the R group would predominate.
All amino acids have two ionizable functional groups: an a-amino group (average pK₁ of 9.4) and an o-carboxylic acid group (average pK₁ of 2.2). Lysine also has an ionizable side chain (R group) with a pK, of about 10.5. One of the possible ionization states of lysine is shown in the image. || H₂N-CH-C-OH I CH₂ 1 CH₂ T Incorrect CH₂ 1 CH₂ +1 NH3 At what pH would the structure be the predominant ionization state? Consider the ionization state of all three of the functional groups. 10.5 The protonated form of the R group of lysine is shown in the structure. The ratio of the charged (protonated) form to the deprotonated form depends on the pK₁ of the R group and the pH of the solution. Select all the pH values at which the charged form of the R group would predominate.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Select all the pH values at which the charged form of the R group would predominate.
* 2.2
* 12.4
* 6.2
* 10.5
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