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acute T cell leukemia. K562 cells were the first human immortalized myelogenous leukemia cell line to be established. Resting= control, Etoposide= drug. Below is shown the results of floweytometry of untreated and treated cells. a Does Etoposide have an effect on Jurkat cells? K562 cells? b. Does the mechanism of action of Etoposide appear to be necrosis or apoptosis?

acute T cell leukemia. K562 cells were the first human immortalized myelogenous leukemia cell line to be established. Resting= control, Etoposide= drug. Below is shown the results of floweytometry of untreated and treated cells. a Does Etoposide have an effect on Jurkat cells? K562 cells? b. Does the mechanism of action of Etoposide appear to be necrosis or apoptosis?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A) Resting Jurkat cells 1 Dead B) Jurkatcells-Etoposide Dead 0:29 Live APO Live АРО 571 10 Annexin V inoA 10 10 Annexin VitcA C) Resting K562 cells 14.86 Dead D) K562 cells-Etoposide fo se Dead 114 Live APO Live АРО 10 onexin VncA Annexin V FincA Legend. Jurkat & K562 cels were incubated with 10uM etoposide for 24h. Resting Jurkat cells A), etoposide treated Jurkat cells B), resting K662 cells C) etoposide treated K562 cells D) were labelled with annexin V-FITC and DAPI (200ng/mi). Courtesy of the Flow Cytometry Core Facility, Blizard Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, E1 2AT. DAP DAP DAP
Transcribed Image Text:A) Resting Jurkat cells 1 Dead B) Jurkatcells-Etoposide Dead 0:29 Live APO Live АРО 571 10 Annexin V inoA 10 10 Annexin VitcA C) Resting K562 cells 14.86 Dead D) K562 cells-Etoposide fo se Dead 114 Live APO Live АРО 10 onexin VncA Annexin V FincA Legend. Jurkat & K562 cels were incubated with 10uM etoposide for 24h. Resting Jurkat cells A), etoposide treated Jurkat cells B), resting K662 cells C) etoposide treated K562 cells D) were labelled with annexin V-FITC and DAPI (200ng/mi). Courtesy of the Flow Cytometry Core Facility, Blizard Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, E1 2AT. DAP DAP DAP
Jurkat cells are an immortalized line of human T-lymphocytes cells that are used to study acute T cell leukemia. K562 cells were the first human immortalized myelogenous leukemia cell line to be established. Resting= control, Etoposide= drug. Below is shown the results of floweytometry of untreated and treated cells. a. Does Etoposide have an effect on Jurkat cells? K562 cells? b. Does the mechanism of action of Etoposide appear to be necrosis or apoptosis?
Transcribed Image Text:Jurkat cells are an immortalized line of human T-lymphocytes cells that are used to study acute T cell leukemia. K562 cells were the first human immortalized myelogenous leukemia cell line to be established. Resting= control, Etoposide= drug. Below is shown the results of floweytometry of untreated and treated cells. a. Does Etoposide have an effect on Jurkat cells? K562 cells? b. Does the mechanism of action of Etoposide appear to be necrosis or apoptosis?
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