Acetazolamide inhibits carbonic anhydrase in a noncompetitive manner, and is used to increase urine output and treat glaucoma, characterized by excessive high pressurewithin the eyeball. The experimental curves of reaction velocity vs. substrate concentration, (CO₂) in μM, are shown in the graphs below, in the presence and absence ofacetazolamide.The Km of carbonic anhydrase for CO2 determined from the data shown is 0.75 μM. From examination of the graphs, deduce that the Km value of carbonic anhydrase forCO₂ in the presence of acetazolamide inhibitor (how does this type of inhibitor affect the Km?).v, initial rate100500A. 0.01 μM.B.0.75 μM.No InhibitorAcetazolamide+ to 100Substrate concentrationOC. 50 μM.OD. 100 μM.E. Not enough information to deduce.

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Acetazolamide inhibits carbonic anhydrase in a noncompetitive manner, and is used to increase urine output and treat glaucoma, characterized by excessive high pressure within the eyeball. The experimental curves of reaction velocity vs. substrate concentration, (CO₂) in μM, are shown in the graphs below, in the presence and absence of acetazolamide. The Km of carbonic anhydrase for CO₂ determined from the data shown is 0.75 μM. From examination of the graphs, deduce that the Km value of carbonic anhydrase for CO₂ in the presence of acetazolamide inhibitor (how does this type of inhibitor affect the Km?). v, initial rate 100 0 A. 0.01 μM. 8.0.75 μM. OC. 50 μM. No Inhibitor Acetazolamide + to 100 Substrate concentration OD. 100 μM. OE. Not enough information to deduce.

Acetazolamide inhibits carbonic anhydrase in a noncompetitive manner, and is used to increase urine output and treat glaucoma, characterized by excessive high pressure within the eyeball. The experimental curves of reaction velocity vs. substrate concentration, (CO₂) in μM, are shown in the graphs below, in the presence and absence of acetazolamide. The Km of carbonic anhydrase for CO₂ determined from the data shown is 0.75 μM. From examination of the graphs, deduce that the Km value of carbonic anhydrase for CO₂ in the presence of acetazolamide inhibitor (how does this type of inhibitor affect the Km?). v, initial rate 100 0 A. 0.01 μM. 8.0.75 μM. OC. 50 μM. No Inhibitor Acetazolamide + to 100 Substrate concentration OD. 100 μM. OE. Not enough information to deduce.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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