Absorbed from the intestines into the blood, nitrites (NO2-) interact with the hemoglobin of the blood and block its respiratory function, turning part of the hemoglobin (HbFe2+) intomethemoglobin (HbFe3+), unable to transfer oxygen from the lungs to tissues. With the formation of a large amount of methemoglobin, oxygen starvation of tissues occurs, which can cause damage to the central nervous system.10 to 20 % - of methemoglobin (HbFe3+) - asymptomatic cyanosis, 20 to 50% of methemoglobin (HbFe3+) -hypoxia develop, > 50% of methemoglobin (HbFe3+) - the person will die.The body weight of the average person is 60 kg. Blood mass averages 8% of a person’s body weight; blood density ρ = 1,050 g/cm3, the hemoglobin (Hb) content in it is 14 g per 100 ml. molecular weight of hemoglobin 65-68 kg/mol (use 68 kg/mol for calculation). Assume that 1 mole of hemoglobin reacts with one mole of nitrite ion to form 1 NO molecule:HbFe2+ + NO2- → HbFe3+ + NOwill a 290 mg dose of sodium nitrite be fatal to the patient? No11 Absorbed from the intestines into the blood, nitrites (NO2") interact with the hemoglobinof the blood and block its respiratory function, turning part of the hemoglobin (HbFe2+) intomethemoglobin (HbFe3+), unable to transfer oxygen from the lungs to tissues. With theformation of a large amount of methemoglobin, oxygen starvation of tissues occurs, which cancause damage to the central nervous system.10 to 20 % - of methemoglobin (HbFe*) - asymptomatic cyanosis,20 to 50% of methemoglobin (HbFe*) - hypoxia develop,> 50% of methemoglobin (HbFe*) - the person will die.The body weight of the average person is 60 kg. Blood mass averages 8% of a person's bodyweight; blood density p = 1,050 g/cm3, the hemoglobin (Hb) content in it is 14 g per 100 ml.molecular weight of hemoglobin 65-68 kg/mol (use 68 kg/mol for calculation). Assume that 1mole of hemoglobin reacts with one mole of nitrite ion to form 1 NO molecule:HbFe2+ + NO2 → HbFe3+ + NOwill a 290 mg dose of sodium nitrite be fatal to the patient?

The number of moles is a ratio of the mass of a substance to the molar mass of the substance.…

Answered: Absorbed from the intestines into the…

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

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Absorbed from the intestines into the blood, nitrites (NO2-) interact with the hemoglobin of the blood and block its respiratory function, turning part of the hemoglobin (HbFe2+) into

methemoglobin (HbFe3+), unable to transfer oxygen from the lungs to tissues. With the formation of a large amount of methemoglobin, oxygen starvation of tissues occurs, which can cause damage to the central nervous system.

10 to 20 % - of methemoglobin (HbFe3+) - asymptomatic cyanosis, 20 to 50% of methemoglobin (HbFe3+) -hypoxia develop, > 50% of methemoglobin (HbFe3+) - the person will die.

The body weight of the average person is 60 kg. Blood mass averages 8% of a person’s body weight; blood density ρ = 1,050 g/cm3, the hemoglobin (Hb) content in it is 14 g per 100 ml. molecular weight of hemoglobin 65-68 kg/mol (use 68 kg/mol for calculation). Assume that 1 mole of hemoglobin reacts with one mole of nitrite ion to form 1 NO molecule:

HbFe2+ + NO2- → HbFe3+ + NO

will a 290 mg dose of sodium nitrite be fatal to the patient?

No11 Absorbed from the intestines into the blood, nitrites (NO2") interact with the hemoglobin
of the blood and block its respiratory function, turning part of the hemoglobin (HbFe2+) into
methemoglobin (HbFe3+), unable to transfer oxygen from the lungs to tissues. With the
formation of a large amount of methemoglobin, oxygen starvation of tissues occurs, which can
cause damage to the central nervous system.
10 to 20 % - of methemoglobin (HbFe*) - asymptomatic cyanosis,
20 to 50% of methemoglobin (HbFe*) - hypoxia develop,
> 50% of methemoglobin (HbFe*) - the person will die.
The body weight of the average person is 60 kg. Blood mass averages 8% of a person's body
weight; blood density p = 1,050 g/cm3, the hemoglobin (Hb) content in it is 14 g per 100 ml.
molecular weight of hemoglobin 65-68 kg/mol (use 68 kg/mol for calculation). Assume that 1
mole of hemoglobin reacts with one mole of nitrite ion to form 1 NO molecule:
HbFe2+ + NO2 → HbFe3+ + NO
will a 290 mg dose of sodium nitrite be fatal to the patient?

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